Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 5/20 | 0.68 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.68 |
| ▸ | CDC25B | P30305 | 2/20 | 0.68 |
| ▸ | IDO1 | P14902 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
| ▸ | SNCA | P37840 | 1/20 | 0.43 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.36 |
| ▸ | FNTA | P49354 | 1/20 | 0.35 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1187716 | 1.00 | PTPN1 (0.68) | PTPN1PTPN2CDC25BIDO1LMNA | |
| SCHEMBL1723760 | 1.00 | PTPN1 (0.68) | PTPN1PTPN2CDC25BIDO1LMNA | |
| SCHEMBL3217423 | 1.00 | PTPN1 (0.68) | PTPN1PTPN2CDC25BIDO1LMNA | |
| SCHEMBL1724050 | 1.00 | PTPN1 (0.68) | PTPN1PTPN2CDC25BIDO1LMNA | |
| SCHEMBL1724226 | 1.00 | PTPN1 (0.68) | PTPN1PTPN2CDC25BIDO1LMNA | |
| SCHEMBL13139046 | 1.00 | PTPN1 (0.68) | PTPN1PTPN2CDC25BIDO1LMNA | |
| SCHEMBL23403885 | 1.00 | PTPN1 (0.68) | PTPN1PTPN2CDC25BIDO1LMNA | |
| SCHEMBL1723665 | 1.00 | PTPN1 (0.68) | PTPN1PTPN2CDC25BIDO1LMNA | |
| SCHEMBL1723691 | 1.00 | PTPN1 (0.68) | PTPN1PTPN2CDC25BIDO1LMNA | |
| SCHEMBL1723689 | 1.00 | PTPN1 (0.68) | PTPN1PTPN2CDC25BIDO1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220055975-A1 | REDOX-ACTIVE THERAPEUTICS FOR TREATMENT OF MITOCHONDRIAL DISEASES AND OTHER CONDITIONS AND MODULATION OF ENERGY BIOMARKERS | PTC THERAPEUTICS, INC. | 2022-02-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220055975-A1 | REDOX-ACTIVE THERAPEUTICS FOR TREATMENT OF MITOCHONDRIAL DISEASES AND OTHER CONDITIONS AND MODULATION OF ENERGY BIOMARKERS | ECHS1, FH, ACAA2 | PTPN1 4752/4885PTPN2 4795/4885CDC25B 4590/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.