SCHEMBL29397266

SCHEMBL29397266

c1cnc2c(n1)c1cncnc1c1nccnc21

nearest known ligand 0.36

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
HSP90AA1 P07900 2/20 0.36
NPC1 O15118 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
CCR1 P32246 1/20 0.32
CCR5 P51681 1/20 0.32
CCR8 P51685 1/20 0.32
EGFR P00533 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29399777 1.00 HSP90AA1 (0.36) HSP90AA1NPC1L3MBTL1CCR1CCR5
SCHEMBL16345858 1.00 HSP90AA1 (0.36) HSP90AA1NPC1L3MBTL1CCR1CCR5
Methane SCHEMBL28329646 0.97 HSP90AA1 (0.34) HSP90AA1NPC1L3MBTL1CCR1CCR5
Fluoromethane SCHEMBL28912319 0.93 HSP90AA1 (0.37) HSP90AA1NPC1L3MBTL1CCR1CCR5
SCHEMBL29151853 0.89 NPC1 (0.30) HSP90AA1NPC1L3MBTL1
SCHEMBL28350921 0.85 PDE10A (0.32)
SCHEMBL21297748 0.84 NPC1 (0.43) HSP90AA1NPC1L3MBTL1CCR1CCR5
SCHEMBL21297742 0.84 NPC1 (0.43) HSP90AA1NPC1L3MBTL1CCR1CCR5
SCHEMBL10820360 0.83 EGFR (0.35) HSP90AA1EGFR
SCHEMBL28815049 0.78 MET (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109689643-B Organic molecules for organic optoelectronic devices 辛诺拉有限公司 2022-03-01 CN disclosed