SCHEMBL29397496

SCHEMBL29397496

CC(C)C[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](N)CCC(=O)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CO)C(=O)O

nearest known ligand 0.63

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ BACE1 P56817 6/20 0.63
▸ KISS1R Q969F8 12/20 0.62
▸ BACE2 Q9Y5Z0 2/20 0.60
▸ OPRD1 P41143 1/20 0.58
▸ NPY1R P25929 1/20 0.57
▸ NPY2R P49146 1/20 0.57
▸ NPY4R P50391 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29440807 0.97 NPY1R (0.59) BACE1KISS1RBACE2OPRD1NPY1R
SCHEMBL18670433 0.95 BACE1 (0.64) BACE1KISS1RBACE2NPY1RNPY2R
SCHEMBL1525876 0.95 BACE1 (0.64) BACE1KISS1RBACE2NPY1RNPY2R
SCHEMBL34471860 0.92 BACE1 (0.67) BACE1KISS1RBACE2NPY1RNPY2R
SCHEMBL29430948 0.92 KISS1R (0.61) BACE1KISS1RBACE2NPY1RNPY2R
SCHEMBL4208913 0.90 BACE1 (0.59) BACE1KISS1RBACE2OPRD1NPY1R
SCHEMBL4208920 0.90 BACE1 (0.59) BACE1KISS1RBACE2OPRD1NPY1R
SCHEMBL32691437 0.90 BACE1 (0.58) BACE1KISS1RBACE2OPRD1NPY1R
SCHEMBL30680475 0.90 NPY1R (0.58) BACE1KISS1RBACE2OPRD1NPY1R
SCHEMBL29730544 0.90 NPY4R (0.58) BACE1KISS1RBACE2NPY1RNPY2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12516089-B2 Bacteria based protein delivery T3 PHARMACEUTICALS AG (CH) 2026-01-06 — — US disclosed
US-12358955-B2 Virulence attenuated bacteria based protein delivery UNIVERSITAET BASEL (CH) 2025-07-15 — — US disclosed
US-20240401065-A1 Bacteria-Based Protein Delivery UNIVERSITAET BASEL (CH) 2024-12-05 — — US disclosed
US-12091670-B2 Bacteria-based protein delivery UNIVERSITAET BASEL (CH) 2024-09-17 — — US disclosed
US-20240165169-A1 Pharmaceutical Combinations for Treating Cancer T3 PHARMACEUTICALS AG (CH) 2024-05-23 — — US disclosed
US-20240165265-A1 Pharmaceutical Combinations for Treating Cancer T3 PHARMACEUTICALS AG (CH) 2024-05-23 — — US disclosed
EP-4314036-A1 PHARMACEUTICAL COMBINATIONS FOR TREATING CANCER T3 Pharmaceuticals AG (CH) 2024-02-07 — — EP disclosed
EP-4313310-A1 PHARMACEUTICAL COMBINATIONS FOR TREATING CANCER T3 Pharmaceuticals AG (CH) 2024-02-07 — — EP disclosed
US-20230382956-A1 BACTERIA BASED PROTEIN DELIVERY T3 PHARMACEUTICALS AG (CH) 2023-11-30 — — US disclosed
US-11827908-B2 Polypeptide having luciferase activity SHIMADZU CORPORATION (JP) 2023-11-28 — — US disclosed
US-11702663-B2 Bacteria-based protein delivery UNIVERSITÄT BASEL (CH) 2023-07-18 — — US disclosed
US-20230148256-A1 EXPRESSION OF MODIFIED PROTEINS IN A PEROXISOME PROVENANCE BIO, LLC 2023-05-11 — — US disclosed
US-11518789-B2 Virulence attenuated bacteria based protein delivery UNIVERSITAET BASEL (CH) 2022-12-06 — — US disclosed
WO-2022200493-A1 PHARMACEUTICAL COMBINATIONS FOR TREATING CANCER T3 PHARMACEUTICALS AG (CH) 2022-09-29 — — WO disclosed
WO-2022200492-A1 PHARMACEUTICAL COMBINATIONS FOR TREATING CANCER T3 PHARMACEUTICALS AG (CH) 2022-09-29 — — WO disclosed
US-20220259575-A1 POLYPEPTIDE HAVING LUCIFERASE ACTIVITY SHIMADZU CORPORATION (JP) 2022-08-18 — — US disclosed
EP-4004196-A2 EXPRESSION OF MODIFIED PROTEINS IN A PEROXISOME Regents of the University of California (US) 2022-06-01 — — EP disclosed
WO-2022090211-A1 BACTERIA BASED PROTEIN DELIVERY T3 PHARMACEUTICALS AG (CH) 2022-05-05 — — WO disclosed
CN-114423861-A Expression of modified proteins in peroxisomes 起源生物有限责任公司 2022-04-29 — — CN disclosed
EP-3957645-A1 VIRULENCE ATTENUATED BACTERIA BASED PROTEIN DELIVERY Universität Basel (CH) 2022-02-23 — — EP disclosed
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