SCHEMBL1525876

SCHEMBL1525876

CC(C)C[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](N)CCC(=O)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCC(N)=O)C(=O)O

nearest known ligand 0.64

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ BACE1 P56817 14/20 0.64
▸ BACE2 Q9Y5Z0 3/20 0.61
▸ NPY1R P25929 1/20 0.58
▸ NPY2R P49146 1/20 0.58
▸ NPY4R P50391 1/20 0.58
▸ CTSD P07339 1/20 0.57
▸ KISS1R Q969F8 4/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18670433 1.00 BACE1 (0.64) BACE1BACE2NPY1RNPY2RNPY4R
SCHEMBL34471860 0.95 BACE1 (0.67) BACE1BACE2NPY1RNPY2RNPY4R
SCHEMBL29397496 0.95 BACE1 (0.63) BACE1BACE2NPY1RNPY2RNPY4R
SCHEMBL31711265 0.93 BACE1 (0.58) BACE1BACE2NPY1RNPY2RNPY4R
SCHEMBL29440807 0.92 NPY1R (0.59) BACE1BACE2NPY1RNPY2RNPY4R
SCHEMBL29549531 0.92 BACE1 (0.60) BACE1BACE2NPY1RNPY2RNPY4R
SCHEMBL30446943 0.92 NPY1R (0.58) BACE1BACE2NPY1RNPY2RNPY4R
SCHEMBL4208913 0.92 BACE1 (0.59) BACE1BACE2NPY1RNPY2RNPY4R
SCHEMBL4208920 0.92 BACE1 (0.59) BACE1BACE2NPY1RNPY2RNPY4R
SCHEMBL29730544 0.91 NPY4R (0.58) BACE1BACE2NPY1RNPY2RNPY4R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 98 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023205728-A2 SOLUBLE SINGLE-CHAIN DIMERS FROM CLEAVABLE SINGLE CHAIN TRIMERS INSTITUTE FOR SYSTEMS BIOLOGY (US) 2023-10-26 — — WO claimed
EP-4748447-A2 INFLUENZA VIRUS VACCINES AND USES THEREOF Icahn School of Medicine at Mount Sinai (US) 2026-05-27 — — EP disclosed
US-20260092925-A1 IMPROVED FLUORESCENT PROTEINS NUCLERA LTD (GB) 2026-04-02 — — US disclosed
US-20260071227-A1 METHOD FOR SECRETORY PRODUCTION OF PROTEINS AJINOMOTO CO., INC. (JP) 2026-03-12 — — US disclosed
US-20260048114-A1 INFLUENZA VIRUS VACCINATION REGIMENS ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (US) 2026-02-19 — — US disclosed
EP-4241785-B1 INFLUENZA VIRUS VACCINES AND USES THEREOF ICAHN SCHOOL MED MOUNT SINAI (US) 2026-01-28 — — EP disclosed
US-20260001918-A1 INFLUENZA VIRUS VACCINES AND USES THEREOF ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (US) 2026-01-01 — — US disclosed
US-20260000747-A1 INFLUENZA VIRUS VACCINES AND USES THEREOF ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (US) 2026-01-01 — — US disclosed
EP-4667580-A1 METHOD FOR SECRETORY PRODUCTION OF PROTEINS AJINOMOTO CO., INC. (JP) 2025-12-24 — — EP disclosed
US-20250382608-A1 LINEAR NUCLEIC ACID EXPRESSION CONSTRUCTS NUCLERA LTD (GB) 2025-12-18 — — US disclosed
US-20220056104-A1 MATERIALS AND METHODS OF USING ENGINEERED LIGANDS JANSSEN BIOTECH, INC. (US) 2022-02-24 — — US disclosed
US-11254733-B2 Anti-influenza B virus neuraminidase antibodies and uses thereof ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (US) 2022-02-22 — — US disclosed
CN-109957560-B Polypeptide with protease activity and application thereof 清华大学 2021-06-29 — — CN disclosed
US-20210017402-A1 ANTI-FOULING PAINTS AND COATINGS REACTIVE SURFACES, LTD., LLP (US) 2021-01-21 — — US disclosed
US-20200354588-A1 ANTI-FOULING PAINTS AND COATINGS REACTIVE SURFACES, LTD., LLP (US) 2020-11-12 — — US disclosed
US-20190203227-A1 LIGHT-CONTROLLED GENE DELIVERY WITH VIRUS VECTORS THROUGH INCORPORATION OF OPTOGENETIC PROTEINS AND GENETIC INSERTION OF NON-CONFORMATIONALLY CONSTRAINED PEPTIDES WILLIAM MARSH RICE UNIVERSITY 2019-07-04 — — US disclosed
CN-109957560-A A kind of polypeptide and its application with proteinase activity 清华大学 2019-07-02 — — CN disclosed
WO-2017053629-A2 LIGHT-CONTROLLED GENE DELIVERY WITH VIRUS VECTORS THROUGH INCORPORATION OF OPTOGENETIC PROTEINS AND GENETIC INSERTION OF NON-CONFORMATIONALLY CONSTRAINED PEPTIDES WILLIAM MARSH RICE UNIVERSITY (US) 2017-03-30 — — WO disclosed
US-20140083324-A1 Anti-fouling Paints and Coatings REACTIVE SURFACES, LTD (US) 2014-03-27 — — US disclosed
US-20110070376-A1 Anti-fouling Paints & Coatings REACTIVE SURFACES, LTD. (US) 2011-03-24 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260071227-A1 METHOD FOR SECRETORY PRODUCTION OF PROTEINS MDH1, MDH2, MLYCD BACE1 4149/4885BACE2 3853/4885NPY1R 1972/4885
US-20260092925-A1 IMPROVED FLUORESCENT PROTEINS YIPF5, YIF1A, GTF3C5 BACE1 3741/4885BACE2 3332/4885NPY1R 460/4885
US-20260000747-A1 INFLUENZA VIRUS VACCINES AND USES THEREOF H1-3, H1-4, H1-2 BACE1 1919/4885BACE2 2429/4885NPY1R 2515/4885
US-20260048114-A1 INFLUENZA VIRUS VACCINATION REGIMENS H1-3, CD81, FUT8 BACE1 1299/4885BACE2 1531/4885NPY1R 4375/4885
US-20250382608-A1 LINEAR NUCLEIC ACID EXPRESSION CONSTRUCTS RNGTT, RNMT, MRPS27 BACE1 4536/4885BACE2 3949/4885NPY1R 4693/4885
US-20260001918-A1 INFLUENZA VIRUS VACCINES AND USES THEREOF CD44, SIGLEC7, SIGLEC9 BACE1 1465/4885BACE2 2251/4885NPY1R 3267/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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