Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | GLA | P06280 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.44 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.44 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.44 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.44 |
| ▸ | AXL | P30530 | 1/20 | 0.44 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.41 |
| ▸ | PREP | P48147 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL827693 | 0.80 | PSMD14 (0.57) | KDM4EALDH1A1GLAPSMD14LMNA | |
| SCHEMBL8415023 | 0.80 | KDM4C (0.52) | KDM4EALDH1A1PSMD14LMNAL3MBTL1 | |
| SCHEMBL5799150 | 0.78 | KDM4E (0.49) | KDM4EALDH1A1GLAGAAL3MBTL1 | |
| SCHEMBL29416299 | 0.77 | KDM4E (0.70) | KDM4EALDH1A1GLAGAALMNA | |
| SCHEMBL68952 | 0.77 | KDM4E (0.70) | KDM4EALDH1A1GLAGAALMNA | |
| SCHEMBL19643044 | 0.76 | NR4A2 (0.50) | KDM4EGLAPSMD14LMNAPREP | |
| SCHEMBL19643450 | 0.76 | CA12 (0.51) | KDM4EALDH1A1GLAGAAPSMD14 | |
| SCHEMBL21056849 | 0.76 | SLC22A12 (0.54) | KDM4EALDH1A1GLAGAAPSMD14 | |
| SCHEMBL15536606 | 0.75 | PSMD14 (0.49) | KDM4EALDH1A1GLAGAAPSMD14 | |
| SCHEMBL1998421 | 0.75 | L3MBTL1 (0.51) | KDM4EALDH1A1GAAPSMD14LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110204544-B | 2- (morpholin-4-yl) -1, 7-naphthyridine | 拜耳制药股份公司 | 2022-04-12 | — | — | CN | disclosed |
| CN-110256427-B | 2- (morpholin-4-yl) -1, 7-naphthyridine | 拜耳制药股份公司 | 2022-02-22 | — | — | CN | disclosed |