SCHEMBL29398142

SCHEMBL29398142

COc1ccc(CN(CC(=O)O)C(=O)[C@@H](CC(=O)OCC2c3ccccc3-c3ccccc32)CC(=O)OC(C)(C)C)c(O)c1

nearest known ligand 0.34

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ POLB P06746 1/20 0.34
▸ TSHR P16473 2/20 0.33
▸ FABP5 Q01469 1/20 0.33
▸ EPHX2 P34913 1/20 0.33
▸ CASP3 P42574 2/20 0.32
▸ PTPN1 P18031 1/20 0.32
▸ MDM2 Q00987 2/20 0.32
▸ SLC6A9 P48067 1/20 0.31
▸ ANO1 Q5XXA6 1/20 0.31
▸ BMP1 P13497 1/20 0.31
▸ GYS1 P13807 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29454464 0.88 MDM2 (0.40) CASP3PTPN1MDM2
SCHEMBL29401351 0.81 POLB (0.43) POLBTSHRFABP5EPHX2PTPN1
SCHEMBL29406617 0.80 MDM2 (0.40) CASP3MDM2
SCHEMBL29363915 0.72 ALDH1A1 (0.46) POLBTSHRFABP5
SCHEMBL28901513 0.72 ALDH1A1 (0.46) POLBTSHRFABP5
SCHEMBL30883356 0.72 PTPN1 (0.38) FABP5PTPN1
SCHEMBL19267609 0.71 KMT2A (0.45) FABP5EPHX2CASP3PTPN1MDM2
SCHEMBL29521277 0.70 KMT2A (0.41) FABP5EPHX2CASP3
SCHEMBL16060098 0.70 KMT2A (0.41) FABP5EPHX2CASP3
SCHEMBL29462650 0.69 PTPN1 (0.46) CASP3PTPN1MDM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119409797-A Tide robust peptide synthesis method 中肽生化有限公司 2025-02-11 — — CN disclosed
EP-4425181-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE Bertis Inc (KR) 2024-09-04 — — EP disclosed
US-20240011979-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTES BERTIS INC. (KR) 2024-01-11 — — US disclosed
CN-116829949-A Compositions for detecting or measuring analytes 伯蒂斯有限公司 2023-09-29 — — CN disclosed
WO-2023075435-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE 주식회사 베르티스 2023-05-04 — — WO disclosed
US-20220283131-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTES BERTIS CO., LTD. (KR) 2022-09-08 — — US disclosed
WO-2022050529-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE ㈜베르티스 2022-03-10 — — WO disclosed
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