Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | SRC | P12931 | 2/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.35 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.35 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.35 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.35 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.35 |
| ▸ | PDE2A | O00408 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22569957 | 1.00 | HTR1A (0.38) | HTR1ATP53KDM4ENPC1RAB9A | |
| SCHEMBL22579639 | 0.87 | PDE2A (0.41) | HTR1ACA1CA2CA9SSTR1 | |
| SCHEMBL22569903 | 0.87 | PDE2A (0.41) | HTR1ACA1CA2CA9SSTR1 | |
| SCHEMBL24557950 | 0.86 | HTR1A (0.37) | HTR1ACA1CA2CA9SSTR1 | |
| SCHEMBL22579642 | 0.85 | HTR1A (0.36) | HTR1ACA1CA2CA9SSTR1 | |
| SCHEMBL22579773 | 0.83 | PTPN1 (0.39) | HTR1ASSTR1SSTR2SSTR4SSTR3 | |
| SCHEMBL18490316 | 0.82 | PDE2A (0.44) | HTR1ACA1CA2CA9SSTR1 | |
| SCHEMBL25379329 | 0.82 | PDE2A (0.44) | HTR1ACA1CA2CA9SSTR1 | |
| SCHEMBL17106846 | 0.82 | PDE2A (0.44) | HTR1ACA1CA2CA9SSTR1 | |
| SCHEMBL17106844 | 0.82 | PDE2A (0.44) | HTR1ACA1CA2CA9SSTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3956341-A1 | CD73 INHIBITORS | Bioardis LLC (US) | 2022-02-23 | — | — | EP | disclosed |