Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | BID | P55957 | 3/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.36 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.36 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.36 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.36 |
| ▸ | IAPP | P10997 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27463142 | 0.95 | TSHR (0.43) | TSHRHTR1AHSPA5POLBMAPK1 | |
| SCHEMBL27813140 | 0.94 | TSHR (0.42) | TSHRHTR1AHSPA5POLBMAPK1 | |
| SCHEMBL27776971 | 0.94 | TSHR (0.42) | TSHRHTR1AHSPA5POLBMAPK1 | |
| SCHEMBL10902230 | 0.93 | TSHR (0.46) | TSHRHTR1AHSPA5POLBMAPK1 | |
| SCHEMBL27798099 | 0.90 | HTR1A (0.42) | TSHRHTR1AHSPA5POLBMAPK1 | |
| SCHEMBL6015484 | 0.88 | TSHR (0.45) | TSHRHTR1AHSPA5POLBMAPK1 | |
| SCHEMBL27813179 | 0.87 | TSHR (0.44) | TSHRHTR1AHSPA5POLBMAPK1 | |
| SCHEMBL27813191 | 0.87 | TSHR (0.44) | TSHRHTR1AHSPA5POLBMAPK1 | |
| SCHEMBL27833253 | 0.87 | TSHR (0.44) | TSHRHTR1AHSPA5POLBMAPK1 | |
| SCHEMBL27980703 | 0.87 | TSHR (0.44) | TSHRHTR1AHSPA5POLBMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109661415-A | The method for reducing the aldehyde discharge of polyurethane foam | 科思创德国股份有限公司 | 2019-04-19 | — | — | CN | claimed |
| CN-101180353-B | Stabilizer blends for improved chlorine resistance | CHEMTURA CORP | 2013-09-11 | — | — | CN | claimed |
| EP-1735412-B1 | KETONE DIARYLAMINE CONDENSATES | CHEMTURA CORP (US) | 2012-03-14 | — | — | EP | claimed |
| CN-1942564-B | Ketone diarylamine condensates | CHEMTURA CORP | 2010-05-05 | — | — | CN | claimed |
| CN-1942564-A | Ketone diarylamine condensates | CHEMTURA CORP (US) | 2007-04-04 | — | — | CN | claimed |
| EP-0274200-B1 | Polyolefins stabilized against oxidative degradation with mixtures of aralkyl-substituted diarylamines and sterically hindered phosphites | UNIROYAL CHEM CO INC (US) | 1994-02-02 | — | — | EP | claimed |
| EP-0309285-A2 | Polypropylene stabilized against oxidative degradation with mixtures of diarylamine derivatives and sterically hindered phenols | UNIROYAL CHEMICAL COMPANY, Inc. (US) | 1989-03-29 | — | — | EP | claimed |
| EP-0274200-A2 | Polyolefins stabilized against oxidative degradation with mixtures of aralkyl-substituted diarylamines and sterically hindered phosphites | UNIROYAL CHEMICAL COMPANY, Inc. (US) | 1988-07-13 | — | — | EP | claimed |
| US-4363745-A | STERICALLY HINDERED PHENOL, BIS(A,A-DIMETHYLBENZYL) DIPHENYLAMINE AND A PHENOTHIAZINE COMPOUND STABILIZERS | THE DOW CHEMICAL COMPANY (US) | 1982-12-14 | — | — | US | claimed |
| US-4275173-A | SYNERGISTIC COMBINATION OF A STERICALLY HINDERED PHENOL AND 4,4*-BIS/A,A-DIMETHYLBENZYL/DIPHENYL AMINE AND A PHENOTHIAZINE PROVIDE OXIDATION RESISTANCE | THE DOW CHEMICAL COMPANY (US) | 1981-06-23 | — | — | US | claimed |
| US-4265783-A | SYNERGISTIC COMBINATION OF STERIC HINDERED PHENOL, 4,4*-BIS/A,A-DIMETHYL BENZYL/DIPHENYLAMINE AND A PHENOTHIAZINE | THE DOW CHEMICAL COMPANY (US) | 1981-05-05 | — | — | US | claimed |
| US-4070304-A | Antioxidant composition, stabilized polyols and polyurethanes prepared therefrom | THE DOW CHEMICAL COMPANY (US) | 1978-01-24 | — | — | US | claimed |
| US-11548997-B2 | Method for the reduction of aldehyde emission in polyurethane foam | HUNTSMAN INTERNATIONAL LLC (US) | 2023-01-10 | — | — | US | disclosed |
| EP-3240817-B1 | REDUCTION OF ALDEHYDES IN AMINE CATALYSTS | HUNTSMAN PETROCHEMICAL LLC (US) | 2021-07-07 | — | — | EP | disclosed |
| EP-3052532-B1 | REDUCTION OF ALDEHYDES IN AMINE CATALYSTS | HUNTSMAN PETROCHEMICAL LLC (US) | 2020-11-11 | — | — | EP | disclosed |
| US-10766994-B2 | Reduction of aldehydes in amine catalysts | HUNTSMAN PETROCHEMICAL LLC (US) | 2020-09-08 | — | — | US | disclosed |
| US-4070304-A | Antioxidant composition, stabilized polyols and polyurethanes prepared therefrom | THE DOW CHEMICAL COMPANY (US) | 1978-01-24 | — | — | US | disclosed |
| US-4070304-A | Antioxidant composition, stabilized polyols and polyurethanes prepared therefrom | THE DOW CHEMICAL COMPANY (US) | 1978-01-24 | — | — | US | disclosed |
| US-4007230-A | A PHENOL AND 4,4'-BIS(ALPHA,ALPHA-DIMETHYLBENZYL)DIPHENYLAMINE | THE DOW CHEMICAL COMPANY (US) | 1977-02-08 | — | — | US | disclosed |
| US-4007230-A | A PHENOL AND 4,4'-BIS(ALPHA,ALPHA-DIMETHYLBENZYL)DIPHENYLAMINE | THE DOW CHEMICAL COMPANY (US) | 1977-02-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10766994-B2 | Reduction of aldehydes in amine catalysts | UNG, ALKBH2, ALKBH3 | TSHR 4663/4885HTR1A 3385/4885HSPA5 2426/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.