Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 6/20 | 0.50 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CLK1 | P49759 | 2/20 | 0.42 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.42 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.42 |
| ▸ | CLK2 | P49760 | 1/20 | 0.42 |
| ▸ | CLK3 | P49761 | 1/20 | 0.42 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.42 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.42 |
| ▸ | GAK | O14976 | 1/20 | 0.42 |
| ▸ | INSR | P06213 | 1/20 | 0.42 |
| ▸ | IGF1R | P08069 | 1/20 | 0.42 |
| ▸ | INSRR | P14616 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL29399656 | 0.94 | LRRK2 (0.49) | LRRK2DYRK1ALMNARECQLKMT2A | |
| SCHEMBL24288494 | 0.93 | LRRK2 (0.52) | LRRK2LMNARECQLKMT2ASLCO1B1 | |
| Trifluoroacetic Acid SCHEMBL30199287 | 0.88 | LRRK2 (0.66) | LRRK2SLCO1B1IGF1RTTKPTK2 | |
| SCHEMBL29399743 | 0.88 | LRRK2 (0.50) | LRRK2DYRK1ALMNARECQLKMT2A | |
| SCHEMBL24288502 | 0.88 | LRRK2 (0.50) | LRRK2DYRK1ALMNARECQLKMT2A | |
| SCHEMBL24288499 | 0.87 | LRRK2 (0.51) | LRRK2DYRK1ALMNARECQLKMT2A | |
| SCHEMBL24288464 | 0.86 | LMNA (0.46) | LRRK2DYRK1ALMNARECQLKMT2A | |
| SCHEMBL29400256 | 0.86 | LMNA (0.46) | LRRK2DYRK1ALMNARECQLKMT2A | |
| Trifluoroacetic Acid SCHEMBL30199374 | 0.84 | LRRK2 (0.62) | LRRK2SLCO1B1IGF1RTTKPTK2 | |
| SCHEMBL24062907 | 0.83 | KMT2A (0.47) | LRRK2LMNARECQLKMT2AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12240844-B2 | Pyrrolopyridine derivative and use thereof in prevention and treatment of protein kinase-related disease | VORONOI, INC. (KR) | 2025-03-04 | — | — | US | claimed |
| US-20220064161-A1 | PYRROLOPYRIDINE DERIVATIVE AND USE THEREOF IN PREVENTION AND TREATMENT OF PROTEIN KINASE-RELATED DISEASE | VORONOI, INC. (KR) | 2022-03-03 | — | — | US | claimed |
| US-12240844-B2 | Pyrrolopyridine derivative and use thereof in prevention and treatment of protein kinase-related disease | VORONOI, INC. (KR) | 2025-03-04 | — | — | US | disclosed |
| US-20220064161-A1 | PYRROLOPYRIDINE DERIVATIVE AND USE THEREOF IN PREVENTION AND TREATMENT OF PROTEIN KINASE-RELATED DISEASE | VORONOI, INC. (KR) | 2022-03-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12240844-B2 | Pyrrolopyridine derivative and use thereof in prevention and treatment of protein kinase-related disease | CLK1, CLK2, CLK3 | LRRK2 5/4885DYRK1A 7/4885LMNA 2483/4885 |
| US-20220064161-A1 | PYRROLOPYRIDINE DERIVATIVE AND USE THEREOF IN PREVENTION AND TREATMENT OF PROTEIN KINASE-RELATED DISEASE | CLK1, CLK2, CLK3 | LRRK2 4/4885DYRK1A 7/4885LMNA 2356/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.