Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 11/20 | 0.66 |
| ▸ | PTK2 | Q05397 | 5/20 | 0.49 |
| ▸ | IGF1R | P08069 | 1/20 | 0.49 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.49 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.48 |
| ▸ | TTK | P33981 | 2/20 | 0.47 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.47 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL30199374 | 0.95 | LRRK2 (0.62) | LRRK2PTK2IGF1RSLCO1B1MAP4K1 | |
| Trifluoroacetic Acid SCHEMBL30199496 | 0.94 | LRRK2 (0.65) | LRRK2PTK2IGF1RSLCO1B1MAP4K1 | |
| SCHEMBL25107212 | 0.93 | LRRK2 (0.70) | LRRK2PTK2IGF1RSLCO1B1MAP4K1 | |
| Trifluoroacetic Acid SCHEMBL30199092 | 0.91 | LRRK2 (0.56) | LRRK2PTK2IGF1RSLCO1B1MAP4K1 | |
| Trifluoroacetic Acid SCHEMBL30198779 | 0.91 | LRRK2 (0.64) | LRRK2PTK2IGF1RSLCO1B1MAP4K1 | |
| Trifluoroacetic Acid SCHEMBL30198979 | 0.90 | LRRK2 (0.56) | LRRK2PTK2IGF1RSLCO1B1MAP4K1 | |
| Trifluoroacetic Acid SCHEMBL30199388 | 0.89 | LRRK2 (0.61) | LRRK2PTK2IGF1RSLCO1B1MAP4K1 | |
| Trifluoroacetic Acid SCHEMBL30199285 | 0.89 | LRRK2 (0.62) | LRRK2PTK2IGF1RSLCO1B1MAP4K1 | |
| Trifluoroacetic Acid SCHEMBL30198703 | 0.89 | LRRK2 (0.55) | LRRK2PTK2IGF1RSLCO1B1MAP4K1 | |
| Trifluoroacetic Acid SCHEMBL29400196 | 0.88 | LRRK2 (0.50) | LRRK2PTK2IGF1RSLCO1B1TTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230066011-A1 | PYRROLOPYRIMIDINE DERIVATIVE, AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING PROTEIN KINASE-RELATED DISEASE COMPRISING SAME AS ACTIVE INGREDIENT | VORONOIBIO CO., LTD. (KR) | 2023-03-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230066011-A1 | PYRROLOPYRIMIDINE DERIVATIVE, AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING PROTEIN KINASE-RELATED DISEASE COMPRISING SAME AS ACTIVE INGREDIENT | LRRK2, BRCA1, PARK7 | LRRK2 1/4885PTK2 92/4885IGF1R 1253/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.