SCHEMBL29400729

SCHEMBL29400729

CC(C)(C)OC(=O)n1cnc(C[C@@H](NC(=O)OCC2c3ccccc3-c3ccccc32)C(=O)O)c1

nearest known ligand 0.57

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ MDM4 O15151 3/20 0.52
▸ TP53 P04637 3/20 0.52
▸ MDM2 Q00987 7/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3439705 1.00 MDM4 (0.52) MDM4TP53MDM2
SCHEMBL21474286 1.00 MDM4 (0.52) MDM4TP53MDM2
SCHEMBL13697504 1.00 MDM4 (0.52) MDM4TP53MDM2
SCHEMBL29386828 1.00 MDM4 (0.52) MDM4TP53MDM2
Cyclohexylamine SCHEMBL29401058 0.92 MDM4 (0.48) MDM4TP53MDM2
Cyclohexylamine SCHEMBL29401401 0.92 MDM4 (0.48) MDM4TP53MDM2
SCHEMBL29401227 0.92 MDM4 (0.56) MDM4TP53MDM2
SCHEMBL29368221 0.92 MDM4 (0.56) MDM4TP53MDM2
SCHEMBL1486207 0.92 MDM4 (0.56) MDM4TP53MDM2
SCHEMBL31382825 0.92 MDM4 (0.46) MDM4TP53MDM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119320430-A Polypeptide PT-1509 and application thereof in antitumor drugs 科通诺贝生物医药科技(北京)有限公司 2025-01-17 — — CN disclosed
CN-118949004-B Bioactive solution and application thereof 天津医科大学 2025-01-14 — — CN disclosed
CN-119192297-A Polypeptide crossing vascular endothelium and selectively anchoring HSCs and application thereof 天津医科大学 2024-12-27 — — CN disclosed
CN-119101127-A Polypeptide for enhancing NK cell immune killing and inhibiting HSCs activation and application thereof 天津医科大学 2024-12-10 — — CN disclosed
CN-118949004-A Bioactive solution and application thereof 天津医科大学 2024-11-15 — — CN disclosed
US-20240011979-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTES BERTIS INC. (KR) 2024-01-11 — — US disclosed
CN-116829949-A Compositions for detecting or measuring analytes 伯蒂斯有限公司 2023-09-29 — — CN disclosed
WO-2023075435-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE 주식회사 베르티스 2023-05-04 — — WO disclosed
US-20230041996-A1 CALCIUM-SENSING RECEPTOR AGONIST COMPOUND AND APPLICATION THEREOF BEIJING TUO JIE BIOPHARMACEUTICAL CO. LTD. (CN) 2023-02-09 — — US disclosed
EP-4091623-A1 CALCIUM-SENSING RECEPTOR AGONIST COMPOUND AND APPLICATION THEREOF Beijing Tuo Jie Biopharmaceutical Co. Ltd. (CN) 2022-11-23 — — EP disclosed
CN-113072622-B Polypeptide for selectively degrading PD-L1 protein on tumor cell membrane and application 南开大学 2022-08-05 — — CN disclosed
WO-2022050529-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE ㈜베르티스 2022-03-10 — — WO disclosed
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