SCHEMBL29386828

SCHEMBL29386828

CC(C)(C)OC(=O)n1cnc(C[C@H](NC(=O)OCC2c3ccccc3-c3ccccc32)C(=O)O)c1

nearest known ligand 0.57

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ MDM4 O15151 3/20 0.52
▸ TP53 P04637 3/20 0.52
▸ MDM2 Q00987 7/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3439705 1.00 MDM4 (0.52) MDM4TP53MDM2
SCHEMBL21474286 1.00 MDM4 (0.52) MDM4TP53MDM2
SCHEMBL29400729 1.00 MDM4 (0.52) MDM4TP53MDM2
SCHEMBL13697504 1.00 MDM4 (0.52) MDM4TP53MDM2
Cyclohexylamine SCHEMBL29401058 0.92 MDM4 (0.48) MDM4TP53MDM2
Cyclohexylamine SCHEMBL29401401 0.92 MDM4 (0.48) MDM4TP53MDM2
SCHEMBL29401227 0.92 MDM4 (0.56) MDM4TP53MDM2
SCHEMBL29368221 0.92 MDM4 (0.56) MDM4TP53MDM2
SCHEMBL1486207 0.92 MDM4 (0.56) MDM4TP53MDM2
SCHEMBL31382825 0.92 MDM4 (0.46) MDM4TP53MDM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 116 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114349827-A Synthetic method of brennuo peptide 江苏诺泰澳赛诺生物制药股份有限公司 2022-04-15 — — CN claimed
CN-114315978-A Method for synthesizing histrelin by solid-liquid method 湖南三太药业有限公司 2022-04-12 — — CN claimed
CN-114276415-A Method for synthesizing leuprorelin by solid-liquid method 湖南三太药业有限公司 2022-04-05 — — CN claimed
CN-114230637-A Method for synthesizing deslorelin by solid and liquid 湖南三太药业有限公司 2022-03-25 — — CN claimed
CN-114181285-A Method for synthesizing nafarelin by solid-liquid method 湖南三太药业有限公司 2022-03-15 — — CN claimed
CN-110294800-B Preparation method of somaglutide 齐鲁制药有限公司 2022-03-04 — — CN claimed
CN-122075734-A Conjugates comprising tetrapeptides, methods of making, intermediates and uses thereof — 2026-05-26 — — CN disclosed
US-12638394-B2 Skin sensitization measuring reagent, method for measuring skin sensitization, and compound FUJIFILM CORPORATION (JP) 2026-05-26 — — US disclosed
EP-3916000-B1 METHOD FOR PRODUCING PEPTIDE COMPOUND, PROTECTING GROUP-FORMING REAGENT, AND AROMATIC HETEROCYCLIC COMPOUND FUJIFILM CORP (JP) 2026-04-08 — — EP disclosed
US-20260077073-A1 GASTRIN-RELEASING PEPTIDE RECEPTOR (GRPR)-TARGETED COMPOUNDS AND USES THEREOF ALPHA 9 ONCOLOGY INC (CA) 2026-03-19 — — US disclosed
EP-3774838-B9 LIXISENATIDE SYNTHESIS WITH CAPPING SANOFI AVENTIS DEUTSCHLAND (DE) 2025-12-10 — — EP disclosed
EP-4655311-A1 METHOD FOR SYNTHESIZING POLYPEPTIDES Boehringer Ingelheim International GmbH (DE) 2025-12-03 — — EP disclosed
US-20250361274-A1 PEPTIDE AND PEPTIDE-CONTAINING AGENT PEPTIDREAM INC. (JP) 2025-11-27 — — US disclosed
CN-114230637-A Method for synthesizing deslorelin by solid and liquid 湖南三太药业有限公司 2022-03-25 — — CN disclosed
CN-114230653-A Preparation method of chlorotoxin 杭州禾泰健宇生物科技有限公司 2022-03-25 — — CN disclosed
CN-114181285-A Method for synthesizing nafarelin by solid-liquid method 湖南三太药业有限公司 2022-03-15 — — CN disclosed
WO-2022050529-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE ㈜베르티스 2022-03-10 — — WO disclosed
CN-110294800-B Preparation method of somaglutide 齐鲁制药有限公司 2022-03-04 — — CN disclosed
EP-3960753-A1 SOLID PHASE PEPTIDE SYNTHESIS METHODS Massachusetts Institute Of Technology (US) 2022-03-02 — — EP disclosed
CN-114075274-A Somarunotide analog and preparation method and application thereof 浙江湃肽生物有限公司深圳分公司 2022-02-22 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12638394-B2 Skin sensitization measuring reagent, method for measuring skin sensitization, and compound HRH1, HRH4, CUTA MDM4 3159/4885TP53 3805/4885MDM2 3842/4885
US-20250361274-A1 PEPTIDE AND PEPTIDE-CONTAINING AGENT BMP4, BMP1, BMPR2 MDM4 3599/4885TP53 3024/4885MDM2 4613/4885
US-20260077073-A1 GASTRIN-RELEASING PEPTIDE RECEPTOR (GRPR)-TARGETED COMPOUNDS AND USES THEREOF GRPR, GIPR, GLP1R MDM4 1761/4885TP53 630/4885MDM2 754/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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