Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM4 | O15151 | 3/20 | 0.52 |
| ▸ | TP53 | P04637 | 3/20 | 0.52 |
| ▸ | MDM2 | Q00987 | 7/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21474286 | 1.00 | MDM4 (0.52) | MDM4TP53MDM2 | |
| SCHEMBL29400729 | 1.00 | MDM4 (0.52) | MDM4TP53MDM2 | |
| SCHEMBL13697504 | 1.00 | MDM4 (0.52) | MDM4TP53MDM2 | |
| SCHEMBL29386828 | 1.00 | MDM4 (0.52) | MDM4TP53MDM2 | |
| Cyclohexylamine SCHEMBL29401058 | 0.92 | MDM4 (0.48) | MDM4TP53MDM2 | |
| Cyclohexylamine SCHEMBL29401401 | 0.92 | MDM4 (0.48) | MDM4TP53MDM2 | |
| SCHEMBL29401227 | 0.92 | MDM4 (0.56) | MDM4TP53MDM2 | |
| SCHEMBL29368221 | 0.92 | MDM4 (0.56) | MDM4TP53MDM2 | |
| SCHEMBL1486207 | 0.92 | MDM4 (0.56) | MDM4TP53MDM2 | |
| SCHEMBL31382825 | 0.92 | MDM4 (0.46) | MDM4TP53MDM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113292430-B | Alpha-carbonyl alkenyl ester compound and preparation method and application thereof | 江西师范大学 | 2022-11-29 | — | — | CN | disclosed |
| CN-113292430-A | Alpha-carbonyl alkenyl ester compound and preparation method and application thereof | 江西师范大学 | 2021-08-24 | — | — | CN | disclosed |
| US-20200347226-A1 | RESIN COMPOSITION FOR INSULATING FILM | NISSAN CHEMICAL CORPORATION (JP) | 2020-11-05 | — | — | US | disclosed |
| US-9150899-B2 | Identification of compounds modifying a cellular response | 2CUREX (DK) | 2015-10-06 | — | — | US | disclosed |
| US-8829153-B2 | Polyimide precursor composition containing polyamic acid alkyl ester | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2014-09-09 | — | — | US | disclosed |
| US-8829153-B2 | Polyimide precursor composition containing polyamic acid alkyl ester | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2014-09-09 | — | — | US | disclosed |
| US-20130123140-A1 | IDENTIFICATION OF COMPOUNDS MODIFYING A CELLULAR RESPONSE | 2CUREX (DK) | 2013-05-16 | — | — | US | disclosed |
| US-8318717-B2 | Tetrapeptide capable of inhibiting binding of the Smac protein to Inhibitors of apoptosis, thus promoting apoptosis or sensitizing cells; antiproliferative and anticarcinogenic agents | 2CUREX (DK) | 2012-11-27 | — | — | US | disclosed |
| US-20120101236-A1 | POLYIMIDE PRECURSOR COMPOSITION CONTAINING POLYAMIC ACID ALKYL ESTER | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2012-04-26 | — | — | US | disclosed |
| US-20120101236-A1 | POLYIMIDE PRECURSOR COMPOSITION CONTAINING POLYAMIC ACID ALKYL ESTER | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2012-04-26 | — | — | US | disclosed |
| US-20090239755-A1 | Identification of Compounds Modifying A Cellular Response | 2CUREX (DK) | 2009-09-24 | — | — | US | disclosed |
| US-20080194537-A1 | Compounds Modifying Apoptosis | 2CUREX (DK) | 2008-08-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080194537-A1 | Compounds Modifying Apoptosis | API5, BAX, BAD | MDM4 486/4885TP53 32/4885MDM2 165/4885 |
| US-20090239755-A1 | Identification of Compounds Modifying A Cellular Response | MCL1, PMAIP1, CDC37 | MDM4 169/4885TP53 18/4885MDM2 360/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.