SCHEMBL29401221

SCHEMBL29401221

CC(C)C[C@H](NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)Oc1c(F)c(F)c(F)c(F)c1F

nearest known ligand 0.65

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ PTPN1 P18031 4/20 0.48
▸ MDM4 O15151 3/20 0.46
▸ TP53 P04637 3/20 0.46
▸ MDM2 Q00987 1/20 0.46
▸ CASP3 P42574 2/20 0.45
▸ KMT2A Q03164 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5706460 1.00 PTPN1 (0.48) PTPN1MDM4TP53MDM2CASP3
SCHEMBL29400612 1.00 PTPN1 (0.48) PTPN1MDM4TP53MDM2CASP3
SCHEMBL29692811 0.91 CTSB (0.48) PTPN1MDM4TP53MDM2CASP3
SCHEMBL2066552 0.89 MDM4 (0.47) MDM4TP53MDM2CASP3KMT2A
SCHEMBL11661459 0.88 PTPN1 (0.46) PTPN1MDM4TP53CASP3KMT2A
SCHEMBL29401144 0.86 CASP3 (0.48) MDM4TP53MDM2CASP3KMT2A
SCHEMBL12798422 0.86 CASP3 (0.48) MDM4TP53MDM2CASP3KMT2A
SCHEMBL7650015 0.86 CASP3 (0.48) MDM4TP53MDM2CASP3KMT2A
SCHEMBL29402434 0.86 CASP3 (0.48) MDM4TP53MDM2CASP3KMT2A
SCHEMBL17525280 0.86 PTPN1 (0.50) PTPN1MDM4TP53CASP3KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110386964-B Solid-liquid synthesis method of leuprorelin 深圳市健元医药科技有限公司 2023-04-07 — — CN claimed
EP-4425181-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE Bertis Inc (KR) 2024-09-04 — — EP disclosed
US-20240011979-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTES BERTIS INC. (KR) 2024-01-11 — — US disclosed
CN-116829949-A Compositions for detecting or measuring analytes 伯蒂斯有限公司 2023-09-29 — — CN disclosed
WO-2023075435-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE 주식회사 베르티스 2023-05-04 — — WO disclosed
CN-110386964-B Solid-liquid synthesis method of leuprorelin 深圳市健元医药科技有限公司 2023-04-07 — — CN disclosed
US-20220307063-A1 METHOD FOR ANALYZING MICROBIAL FLORA NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 2022-09-29 — — US disclosed
US-20220283131-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTES BERTIS CO., LTD. (KR) 2022-09-08 — — US disclosed
WO-2022050529-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE ㈜베르티스 2022-03-10 — — WO disclosed
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