SCHEMBL2940189

SCHEMBL2940189

CC(=O)OC1C(C(C)C)=Cc2ccccc21

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.44
ALDH1A1 P00352 4/20 0.35
LMNA P02545 2/20 0.35
ALOX5 P09917 1/20 0.35
TDP1 Q9NUW8 3/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
P2RX1 P51575 1/20 0.34
P2RX3 P56373 1/20 0.34
P2RX4 Q99571 1/20 0.34
P2RX7 Q99572 1/20 0.34
RET P07949 1/20 0.33
HPGD P15428 2/20 0.32
CHRM2 P08172 3/20 0.31
CHRM4 P08173 3/20 0.31
CHRM5 P08912 3/20 0.31
CHRM1 P11229 3/20 0.31
CHRM3 P20309 3/20 0.31
TSHR P16473 2/20 0.30
KDM4E B2RXH2 1/20 0.30
ESR1 P03372 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2937446 0.82 POLB (0.47) POLBALDH1A1LMNAALOX5TDP1
SCHEMBL10739253 0.80 RET (0.37) ALDH1A1LMNAP2RX1P2RX3P2RX4
SCHEMBL2934277 0.75 POLB (0.44) POLBALDH1A1LMNAALOX5TDP1
SCHEMBL11500090 0.72 POLB (0.41) POLBALDH1A1LMNAALOX5TDP1
SCHEMBL27357700 0.70 POLB (0.45) POLBALDH1A1P2RX1P2RX3P2RX4
SCHEMBL2943498 0.70 CYP3A4 (0.46) POLBALDH1A1LMNATDP1SMN1; SMN2
SCHEMBL29866017 0.69 MEN1 (0.32) SMN1; SMN2HPGDPTGS2
SCHEMBL5175325 0.69 TSHR (0.47) POLBALDH1A1LMNATDP1TSHR
SCHEMBL30341829 0.69 POLB (0.71) POLBALDH1A1LMNAHPGDTSHR
SCHEMBL4402923 0.69 POLB (0.71) POLBALDH1A1LMNAHPGDTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1756027-B1 PROCESS FOR PRODUCING INDENOL ESTERS OR ETHERS FIRMENICH & CIE (CH) 2010-09-22 EP disclosed
CN-1953952-B Process for producing indenol esters or ethers FIRMENICH & CIE 2010-08-11 CN disclosed
US-7250528-B2 Process for producing indenol esters or ethers FIRMENICH SA (CH) 2007-07-31 US disclosed
CN-1953952-A Process for producing indenol esters or ethers FIRMENICH & CIE (CH) 2007-04-25 CN disclosed
EP-1756027-A2 PROCESS FOR PRODUCING INDENOL ESTERS OR ETHERS FIRMENICH SA (CH) 2007-02-28 EP disclosed
US-20070032402-A1 Process for producing indenol esters or ethers FIRMENICH SA (CH) 2007-02-08 US disclosed
WO-2005113473-A2 PROCESS FOR PRODUCING INDENOL ESTERS OR ETHERS FIRMENICH SA (CH) 2005-12-01 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070032402-A1 Process for producing indenol esters or ethers NISCH, SULT2A1, SI POLB 4549/4885ALDH1A1 120/4885LMNA 1616/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.