Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM4 | O15151 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 3/20 | 0.44 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MDM2 | Q00987 | 5/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30262995 | 1.00 | MDM4 (0.44) | MDM4TP53PIN1CASP3KMT2A | |
| SCHEMBL25817017 | 1.00 | MDM4 (0.44) | MDM4TP53PIN1CASP3KMT2A | |
| SCHEMBL22892703 | 0.85 | MDM2 (0.40) | MDM4TP53PIN1KMT2AMDM2 | |
| SCHEMBL28708945 | 0.85 | MDM2 (0.40) | MDM4TP53PIN1KMT2AMDM2 | |
| SCHEMBL25816905 | 0.84 | MDM4 (0.42) | MDM4TP53PIN1CASP3MDM2 | |
| SCHEMBL30517361 | 0.84 | MDM4 (0.42) | MDM4TP53PIN1CASP3MDM2 | |
| SCHEMBL30262997 | 0.84 | MDM4 (0.42) | MDM4TP53PIN1CASP3MDM2 | |
| SCHEMBL29812637 | 0.84 | MDM4 (0.43) | MDM4TP53CASP3KMT2AMDM2 | |
| SCHEMBL25817023 | 0.80 | KMT2A (0.45) | MDM4TP53CASP3KMT2A | |
| SCHEMBL15966524 | 0.79 | PTPN1 (0.42) | MDM4TP53PIN1MDM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115715294-A | Method for synthesizing thioether-containing peptides | 海德堡医药研究有限责任公司 | 2023-02-24 | — | — | CN | disclosed |
| CN-114080395-A | Synthesis method of alpha-amanitine and derivatives thereof | 纯生物有机有限公司 | 2022-02-22 | — | — | CN | disclosed |