Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM4 | O15151 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | MDM2 | Q00987 | 6/20 | 0.39 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | GRB2 | P62993 | 1/20 | 0.38 |
| ▸ | PRCP | P42785 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30262997 | 1.00 | MDM4 (0.42) | MDM4TP53MDM2PIN1CASP3 | |
| SCHEMBL30517361 | 1.00 | MDM4 (0.42) | MDM4TP53MDM2PIN1CASP3 | |
| SCHEMBL25816930 | 0.89 | MDM4 (0.43) | MDM4TP53MDM2PIN1CASP3 | |
| SCHEMBL29402078 | 0.84 | MDM4 (0.44) | MDM4TP53MDM2PIN1CASP3 | |
| SCHEMBL25817017 | 0.84 | MDM4 (0.44) | MDM4TP53MDM2PIN1CASP3 | |
| SCHEMBL30262995 | 0.84 | MDM4 (0.44) | MDM4TP53MDM2PIN1CASP3 | |
| SCHEMBL30517343 | 0.82 | FABP5 (0.39) | MDM4TP53 | |
| SCHEMBL25816888 | 0.82 | FABP5 (0.39) | MDM4TP53 | |
| SCHEMBL27443954 | 0.77 | CASP3 (0.39) | MDM4TP53PIN1CASP3PRCP | |
| SCHEMBL1157170 | 0.77 | MDM2 (0.46) | MDM4TP53MDM2CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230220001-A1 | METHOD FOR SYNTHESIS OF THIOETHER-CONTAINING PEPTIDES | HEIDELBERG PHARMA RESEARCH GMBH (DE) | 2023-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230220001-A1 | METHOD FOR SYNTHESIS OF THIOETHER-CONTAINING PEPTIDES | TST, PTMS, CTH | MDM4 1730/4885TP53 1979/4885MDM2 1523/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.