Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 4/20 | 0.54 |
| ▸ | MDM4 | O15151 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21416122 | 1.00 | CASP3 (0.54) | CASP3MDM4TP53KMT2APIN1 | |
| SCHEMBL25717715 | 1.00 | CASP3 (0.54) | CASP3MDM4TP53KMT2APIN1 | |
| SCHEMBL21403415 | 1.00 | CASP3 (0.54) | CASP3MDM4TP53KMT2APIN1 | |
| SCHEMBL25717723 | 1.00 | CASP3 (0.54) | CASP3MDM4TP53KMT2APIN1 | |
| SCHEMBL25717714 | 1.00 | CASP3 (0.54) | CASP3MDM4TP53KMT2APIN1 | |
| SCHEMBL21403417 | 1.00 | CASP3 (0.54) | CASP3MDM4TP53KMT2APIN1 | |
| SCHEMBL13227980 | 0.88 | CASP3 (0.51) | CASP3MDM4TP53KMT2AEPHX2 | |
| SCHEMBL120703 | 0.88 | CASP3 (0.60) | CASP3MDM4TP53KMT2APIN1 | |
| SCHEMBL30307097 | 0.88 | CASP3 (0.60) | CASP3MDM4TP53KMT2APIN1 | |
| SCHEMBL799720 | 0.88 | CASP3 (0.60) | CASP3MDM4TP53KMT2APIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112585116-B | Synthesis of (2S, 3R, 4R) -4, 5-dihydroxyisoleucine and derivatives thereof | 海德堡医药研究有限责任公司 | 2024-05-14 | — | — | CN | disclosed |
| CN-114080395-A | Synthesis method of alpha-amanitine and derivatives thereof | 纯生物有机有限公司 | 2022-02-22 | — | — | CN | disclosed |