SCHEMBL120703

SCHEMBL120703

CC(C)[C@H](NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)O

nearest known ligand 0.60

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CASP3 P42574 4/20 0.60
KMT2A Q03164 2/20 0.52
MDM4 O15151 2/20 0.52
TP53 P04637 2/20 0.52
EPHX2 P34913 1/20 0.49
PIN1 Q13526 1/20 0.48
MDM2 Q00987 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29356434 1.00 CASP3 (0.60) CASP3KMT2AMDM4TP53EPHX2
SCHEMBL29375252 1.00 CASP3 (0.60) CASP3KMT2AMDM4TP53EPHX2
SCHEMBL30307097 1.00 CASP3 (0.60) CASP3KMT2AMDM4TP53EPHX2
SCHEMBL799720 1.00 CASP3 (0.60) CASP3KMT2AMDM4TP53EPHX2
SCHEMBL178791 1.00 CASP3 (0.60) CASP3KMT2AMDM4TP53EPHX2
SCHEMBL29423588 1.00 CASP3 (0.60) CASP3KMT2AMDM4TP53EPHX2
SCHEMBL31697682 1.00 CASP3 (0.60) CASP3KMT2AMDM4TP53EPHX2
Hydrochloric Acid SCHEMBL6779156 0.99 CASP3 (0.59) CASP3KMT2AMDM4TP53EPHX2
Fluoride SCHEMBL7158848 0.99 CASP3 (0.59) CASP3KMT2AMDM4TP53EPHX2
SCHEMBL29068310 0.95 CASP3 (0.64) CASP3KMT2AMDM4TP53EPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 775 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119901859-A Analysis method for purity of fluorenylmethoxycarbonyl-L-valine and related substances 苏州默迪夫生物科技有限公司 2025-04-29 CN claimed
US-20240351975-A1 METHODS OF SYNTHESIZING 4-VALYLOXYBUTYRIC ACID XWPharma Ltd. (KY) 2024-10-24 US claimed
CN-117924414-A Compound for promoting Abeta clearance and preparation method and application thereof 中山大学 2024-04-26 CN claimed
CN-114456234-B Antioxidant lipopeptides, preparation method and application thereof 中国石油大学(华东) 2023-06-30 CN claimed
CN-114456234-A Antioxidant lipopeptide and preparation method and application thereof 中国石油大学(华东) 2022-05-10 CN claimed
EP-3988538-A1 MODIFIED HYDROPHOBIC AUXILIARY MATERIAL, PREPARATION METHOD THEREFOR AND USE THEREOF Zhejiang Zhida Pharmaceutical Co., Ltd. (CN) 2022-04-27 EP claimed
US-20220111055-A1 MODIFIED HYDROPHOBIC EXCIPIENT AND PREPARATION METHOD THEREOF ZHEJIANG ZHIDA PHARMACEUTICAL CO., LTD. (CN) 2022-04-14 US claimed
CN-110054574-B Synthesis method of fluorenylmethyloxycarbonyl-2, 3-dehydro-valine 上海吉奉生物科技有限公司 2021-08-20 CN claimed
WO-2020252713-A1 MODIFIED HYDROPHOBIC AUXILIARY MATERIAL, PREPARATION METHOD THEREFOR AND USE THEREOF 浙江智达药业有限公司 2020-12-24 WO claimed
CN-112110834-A Modified hydrophobic auxiliary material and preparation method and application thereof 浙江智达药业有限公司 2020-12-22 CN claimed
CN-108440654-B Synthesis method of antibacterial active cyclic hexapeptide Thermoactinamide A 暨南大学 2020-09-04 CN claimed
CN-108373496-A Inoxidizability polypeptide GTMGAVGPRG and preparation method thereof 安徽工程大学 2018-08-07 CN claimed
CN-103626844-B Artificially synthesized wheat germ peptide and preparation method and application thereof CHANGSHA UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) 2015-08-19 CN claimed
CN-103626844-A Artificially synthesized wheat germ peptide and preparation method and application thereof UNIV CHANGSHA SCIENCE 2014-03-12 CN claimed
EP-4748847-A1 PEPTIDE COMPLEX HAVING VEGFR -2 AGONIST ACTIVITY Peptidream Inc (JP) 2026-05-27 EP disclosed
EP-4029868-B1 MCL-1 INHIBITORS GILEAD SCIENCES INC (US) 2026-05-20 EP disclosed
EP-3972649-B1 MCL-1 INHIBITOR ANTIBODY-DRUG CONJUGATES AND METHODS OF USE NOVARTIS AG (CH) 2026-05-13 EP disclosed
WO-1989008643-A1 URETHANE-PROTECTED AMINO ACID-N-CARBOXYANHYDRIDES BIORESEARCH, INC. (US) 1989-09-21 WO disclosed
EP-0305929-A2 Membranes with bound oligonucleotides and peptides MILLIPORE CORPORATION (US) 1989-03-08 EP disclosed
US-4108846-A FOR PRODUCTION OF POLYPEPTIDES HOFFMANN-LA ROCHE INC. 1978-08-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240351975-A1 METHODS OF SYNTHESIZING 4-VALYLOXYBUTYRIC ACID GABBR1, GABBR2, GABRB3 CASP3 2672/4885KMT2A 2039/4885MDM4 1218/4885
US-20220111055-A1 MODIFIED HYDROPHOBIC EXCIPIENT AND PREPARATION METHOD THEREOF CETP, SLC43A1, SLC27A1 CASP3 2158/4885KMT2A 2845/4885MDM4 884/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.