SCHEMBL29402299

SCHEMBL29402299

O=C(N[C@H](Cc1ccc(Cl)c(Cl)c1)C(=O)O)OCC1c2ccccc2-c2ccccc21

nearest known ligand 0.58

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ FPR2 P25090 1/20 0.53
▸ MDM4 O15151 3/20 0.52
▸ TP53 P04637 3/20 0.52
▸ PTPN1 P18031 3/20 0.47
▸ MDM2 Q00987 4/20 0.47
▸ CASP3 P42574 2/20 0.47
▸ SLC17A5 Q9NRA2 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL119512 1.00 FPR2 (0.53) FPR2MDM4TP53PTPN1MDM2
SCHEMBL29907959 1.00 FPR2 (0.53) FPR2MDM4TP53PTPN1MDM2
SCHEMBL3366913 1.00 FPR2 (0.53) FPR2MDM4TP53PTPN1MDM2
SCHEMBL119309 1.00 FPR2 (0.53) FPR2MDM4TP53PTPN1MDM2
SCHEMBL31369603 0.92 MDM4 (0.52) MDM4TP53PTPN1MDM2CASP3
SCHEMBL27101546 0.92 CA2 (0.51) MDM4TP53PTPN1MDM2CASP3
SCHEMBL30898985 0.92 CA2 (0.51) MDM4TP53PTPN1MDM2CASP3
SCHEMBL2578833 0.92 CA2 (0.51) MDM4TP53PTPN1MDM2CASP3
SCHEMBL29400332 0.92 CA2 (0.51) MDM4TP53PTPN1MDM2CASP3
SCHEMBL16095683 0.91 MDM2 (0.51) FPR2MDM4TP53PTPN1MDM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3303367-B1 STABILIZED MINIMAL COILED-COIL MIMETICS UNIV NEW YORK (US) 2025-06-18 — — EP disclosed
CN-114874293-B Cyclic polypeptide compound and preparation method and application thereof 中国医学科学院医药生物技术研究所 2025-05-23 — — CN disclosed
EP-4425181-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE Bertis Inc (KR) 2024-09-04 — — EP disclosed
US-20240124539-A1 CROSSLINKED HELIX DIMER MIMICS OF SOS AND METHODS OF USING SAME NEW YORK UNIVERSITY 2024-04-18 — — US disclosed
US-20240011979-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTES BERTIS INC. (KR) 2024-01-11 — — US disclosed
WO-2023075435-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE 주식회사 베르티스 2023-05-04 — — WO disclosed
US-20220283131-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTES BERTIS CO., LTD. (KR) 2022-09-08 — — US disclosed
WO-2022050529-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE ㈜베르티스 2022-03-10 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240124539-A1 CROSSLINKED HELIX DIMER MIMICS OF SOS AND METHODS OF USING SAME SOS2, SOS1, F2 FPR2 428/4885MDM4 2834/4885TP53 2795/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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