Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | GRM5 | P41594 | 6/20 | 0.49 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.45 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24571464 | 1.00 | MAPT (0.50) | MAPTGRM5NTRK1RAB9ATRPV1 | |
| SCHEMBL22659819 | 0.85 | MCHR1 (0.41) | NTRK1TRPV1MCHR1HTR2C | |
| SCHEMBL22659299 | 0.83 | NTRK1 (0.49) | MAPTGRM5NTRK1RAB9ATRPV1 | |
| SCHEMBL29403375 | 0.83 | NTRK1 (0.49) | MAPTGRM5NTRK1RAB9ATRPV1 | |
| SCHEMBL22659356 | 0.82 | NTRK1 (0.51) | MAPTGRM5NTRK1RAB9APOLB | |
| SCHEMBL22659881 | 0.80 | ABL1 (0.46) | MAPTGRM5NTRK1MCHR1HTR2C | |
| SCHEMBL24571207 | 0.79 | ABL1 (0.42) | MAPTGRM5NTRK1 | |
| SCHEMBL24571213 | 0.77 | NTRK1 (0.47) | MAPTGRM5NTRK1MCHR1HTR2C | |
| SCHEMBL29406420 | 0.77 | NTRK1 (0.47) | MAPTGRM5NTRK1MCHR1HTR2C | |
| SCHEMBL24571337 | 0.76 | SCN9A (0.45) | NTRK1TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3966208-A2 | COMPOUNDS AND METHODS FOR TREATING CANCER | Antidote IP Holdings, LLC (US) | 2022-03-16 | — | — | EP | disclosed |