Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CTRC | Q99895 | 1/20 | 0.34 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.32 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.32 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.32 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1188816 | 1.00 | TDP1 (0.44) | TDP1CTRCGRIN2DGRIN3BGRIN1 | |
| SCHEMBL30500471 | 0.82 | TDP1 (0.41) | TDP1ALDH1A1PKM | |
| SCHEMBL7832945 | 0.82 | TDP1 (0.41) | TDP1ALDH1A1PKM | |
| SCHEMBL16454767 | 0.79 | GRIN2D (0.35) | CTRCGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL2259889 | 0.79 | TDP1 (0.33) | TDP1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL1268563 | 0.79 | TDP1 (0.39) | TDP1CTRCRAB9A | |
| SCHEMBL29993398 | 0.77 | TDP1 (0.41) | TDP1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL3024535 | 0.77 | TDP1 (0.41) | TDP1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL3012650 | 0.77 | NOS3 (0.39) | TDP1CTRCGRIN2DGRIN3BGRIN1 | |
| SCHEMBL5567705 | 0.77 | TDP1 (0.38) | TDP1CTRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119300833-A | Novel compounds | 豪夫迈·罗氏有限公司 | 2025-01-10 | — | — | CN | disclosed |
| CN-118265701-A | Pyridazine derivatives as inhibitors of NLRP3 | 豪夫迈·罗氏有限公司 | 2024-06-28 | — | — | CN | disclosed |
| CN-114072390-B | RAD51 inhibitors | 赛泰尔治疗公司 | 2024-06-11 | — | — | CN | disclosed |
| CN-111566089-B | IRE1 small molecule inhibitors | 康奈尔大学 | 2023-11-17 | — | — | CN | disclosed |
| CN-114072390-A | RAD51 inhibitors | 赛泰尔治疗公司 | 2022-02-18 | — | — | CN | disclosed |