Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.50 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.46 |
| ▸ | PSEN1 | P49768 | 4/20 | 0.42 |
| ▸ | PSEN2 | P49810 | 4/20 | 0.42 |
| ▸ | APH1B | Q8WW43 | 4/20 | 0.42 |
| ▸ | NCSTN | Q92542 | 4/20 | 0.42 |
| ▸ | APH1A | Q96BI3 | 4/20 | 0.42 |
| ▸ | PSENEN | Q9NZ42 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9017695 | 0.79 | EPHX1 (0.54) | EPHX1GRM4PSEN1PSEN2APH1B | |
| SCHEMBL24209275 | 0.79 | EPHX1 (0.54) | EPHX1GRM4PSEN1PSEN2APH1B | |
| SCHEMBL9800070 | 0.78 | EPHX1 (0.67) | EPHX1GRM4PSEN1PSEN2APH1B | |
| SCHEMBL13557474 | 0.78 | EPHX1 (0.67) | EPHX1GRM4PSEN1PSEN2APH1B | |
| SCHEMBL1570434 | 0.78 | EPHX1 (0.67) | EPHX1GRM4PSEN1PSEN2APH1B | |
| SCHEMBL9800227 | 0.78 | EPHX1 (0.67) | EPHX1GRM4PSEN1PSEN2APH1B | |
| SCHEMBL17205447 | 0.78 | EPHX1 (0.67) | EPHX1GRM4PSEN1PSEN2APH1B | |
| SCHEMBL15128791 | 0.75 | ADAM10 (0.32) | EPHX1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL4818915 | 0.74 | TAAR1 (0.39) | EPHX1GRM4PSEN1PSEN2APH1B | |
| SCHEMBL13527464 | 0.74 | HDAC8 (0.50) | EPHX1ALDH1A1LMNAKDM4ETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110114349-B | Thiophene derivatives as antiviral agents | 埃尼奥制药公司 | 2022-03-15 | — | — | CN | disclosed |