Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | KLKB1 | P03952 | 5/20 | 0.43 |
| ▸ | F11 | P03951 | 6/20 | 0.43 |
| ▸ | F2 | P00734 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21145582 | 1.00 | ALDH1A1 (0.51) | ALDH1A1TSHRKMT2ALMNAKDM4E | |
| SCHEMBL19668371 | 0.88 | KMT2A (0.44) | ALDH1A1TSHRKMT2ALMNAKDM4E | |
| SCHEMBL17221299 | 0.88 | ALDH1A1 (0.55) | ALDH1A1TSHRKMT2ALMNAKDM4E | |
| SCHEMBL30665150 | 0.88 | ALDH1A1 (0.52) | ALDH1A1TSHRKMT2ALMNAKDM4E | |
| SCHEMBL17232505 | 0.88 | ALDH1A1 (0.52) | ALDH1A1TSHRKMT2ALMNAKDM4E | |
| SCHEMBL29697621 | 0.88 | ALDH1A1 (0.55) | ALDH1A1TSHRKMT2ALMNAKDM4E | |
| SCHEMBL17221253 | 0.86 | ALDH1A1 (0.51) | ALDH1A1TSHRKMT2ALMNAKDM4E | |
| SCHEMBL21355200 | 0.86 | ALDH1A1 (0.51) | ALDH1A1TSHRKMT2ALMNAKDM4E | |
| Hydrochloric Acid SCHEMBL21354812 | 0.86 | ALDH1A1 (0.53) | ALDH1A1TSHRKMT2ALMNAKDM4E | |
| SCHEMBL29792688 | 0.86 | ALDH1A1 (0.51) | ALDH1A1TSHRKMT2ALMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114206852-A | Plasma kallikrein inhibitors | 卡尔维斯塔制药有限公司 | 2022-03-18 | — | — | CN | disclosed |