SCHEMBL29406993

SCHEMBL29406993

CC(C)c1cccc(C#C[Si](C)(C)C)c1C#C[Si](C)(C)C

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 3/20 0.36
CYP1A2 P05177 2/20 0.36
CYP3A4 P08684 2/20 0.36
HPGD P15428 2/20 0.36
TSHR P16473 2/20 0.36
GABRG2 P18507 2/20 0.36
GABRB3 P28472 2/20 0.36
GABRB2 P47870 2/20 0.36
FAAH O00519 1/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
LMNA P02545 1/20 0.36
GABRB1 P18505 1/20 0.36
PTGS1 P23219 1/20 0.36
SLC6A2 P23975 1/20 0.36
HTR2C P28335 1/20 0.36
GABRA5 P31644 1/20 0.36
GABRA3 P34903 1/20 0.36
HTR2B P41595 1/20 0.36
GABRA2 P47869 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4095370 0.83 CYP1A2 (0.41) GABRA1CYP1A2CYP3A4HPGDTSHR
SCHEMBL3845195 0.82 KDM4E (0.41) CYP1A2CYP3A4HPGDTSHRKDM4E
SCHEMBL28468438 0.74 KDM4E (0.36) CYP1A2CYP3A4HPGDTSHRKDM4E
SCHEMBL28728194 0.73 KDM4E (0.42) GABRA1CYP1A2CYP3A4HPGDTSHR
SCHEMBL3839029 0.71 KDM4E (0.49) GABRA1CYP1A2CYP3A4HPGDTSHR
SCHEMBL2856342 0.70 ALDH1A1 (0.40) GABRA1CYP1A2CYP3A4HPGDTSHR
SCHEMBL1626479 0.70 ALDH1A1 (0.37) CYP1A2CYP3A4HPGDTSHRKDM4E
SCHEMBL12477380 0.70 CREBBP (0.36) CYP1A2CYP3A4HPGDTSHRKDM4E
SCHEMBL20626280 0.69 KDM4E (0.33) CYP1A2CYP3A4HPGDTSHRKDM4E
SCHEMBL31736077 0.68 KDM4E (0.37) CYP1A2CYP3A4HPGDTSHRKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114106338-A Silicon aryne resin with p-diacetylene diphenylmethane structure and composite material and preparation method thereof 华东理工大学 2022-03-01 CN disclosed