SCHEMBL29407201

SCHEMBL29407201

CCN(CC)c1cccc(NS(C)(=O)=O)c1

nearest known ligand 0.68

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
NR3C1 P04150 1/20 0.68
NR3C2 P08235 3/20 0.54
ALDH1A1 P00352 5/20 0.49
SMN1; SMN2 Q16637 2/20 0.49
KEAP1 Q14145 1/20 0.48
HSP90AA1 P07900 1/20 0.48
HSP90AB1 P08238 1/20 0.48
CYP3A4 P08684 2/20 0.47
KIF11 P52732 1/20 0.47
POLB P06746 1/20 0.46
HTR7 P34969 2/20 0.45
HTT P42858 2/20 0.44
LMNA P02545 1/20 0.44
TP53 P04637 1/20 0.42
CYP1A2 P05177 1/20 0.42
ALOX15 P16050 1/20 0.42
TSHR P16473 1/20 0.42
MAPK1 P28482 1/20 0.42
HSD17B10 Q99714 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5945125 1.00 NR3C1 (0.68) NR3C1NR3C2ALDH1A1SMN1; SMN2KEAP1
Hydrochloric Acid SCHEMBL11059615 0.98 NR3C1 (0.67) NR3C1NR3C2ALDH1A1SMN1; SMN2KEAP1
SCHEMBL30280484 0.87 NR3C1 (0.65) NR3C1NR3C2ALDH1A1SMN1; SMN2KEAP1
SCHEMBL28974174 0.87 NR3C1 (0.65) NR3C1NR3C2ALDH1A1SMN1; SMN2KEAP1
SCHEMBL10894219 0.87 NR3C1 (0.87) NR3C1NR3C2KEAP1TSHR
SCHEMBL8713187 0.87 NR3C1 (0.52) NR3C1ALDH1A1SMN1; SMN2CYP3A4HTT
SCHEMBL11439452 0.85 NR3C1 (0.55) NR3C1NR3C2ALDH1A1SMN1; SMN2KEAP1
SCHEMBL11409417 0.84 HTT (0.54) NR3C1ALDH1A1SMN1; SMN2CYP3A4POLB
SCHEMBL3507875 0.83 CA2 (0.54) NR3C1ALDH1A1SMN1; SMN2CYP3A4HTT
SCHEMBL28038520 0.83 NR3C1 (0.63) NR3C1NR3C2ALDH1A1SMN1; SMN2KEAP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114106580-A Environment-friendly azo red dye disperse red 343 with excellent application performance and preparation method thereof 安徽清科瑞洁新材料有限公司 2022-03-01 CN claimed
CN-114106580-A Environment-friendly azo red dye disperse red 343 with excellent application performance and preparation method thereof 安徽清科瑞洁新材料有限公司 2022-03-01 CN disclosed