Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK1 | Q9BUB5 | 5/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 6/20 | 0.35 |
| ▸ | SOS1 | Q07889 | 4/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.34 |
| ▸ | OXTR | P30559 | 1/20 | 0.34 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23326447 | 1.00 | MKNK1 (0.36) | MKNK1POLBPIK3CDSOS1GABRA1 | |
| SCHEMBL23345273 | 0.75 | SOS1 (0.68) | SOS1 | |
| SCHEMBL22676898 | 0.75 | POLB (0.37) | POLBPIK3CD | |
| SCHEMBL29407675 | 0.75 | POLB (0.37) | POLBPIK3CD | |
| SCHEMBL24672117 | 0.75 | JAK2 (0.43) | PIK3CD | |
| SCHEMBL30556399 | 0.71 | JAK2 (0.42) | POLBPIK3CDSOS1 | |
| SCHEMBL23326798 | 0.70 | SOS1 (0.46) | SOS1 | |
| SCHEMBL29861298 | 0.70 | SOS1 (0.46) | SOS1 | |
| SCHEMBL30692962 | 0.70 | MKNK1 (0.38) | MKNK1POLBSOS1ESR2 | |
| SCHEMBL22676756 | 0.69 | JAK2 (0.36) | POLBPIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114901662-A | Bicyclic heteroaryl compounds and uses thereof | 锐新医药公司 | 2022-08-12 | — | — | CN | disclosed |