Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 9/20 | 0.42 |
| ▸ | CYP4A11 | Q02928 | 9/20 | 0.42 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.40 |
| ▸ | TGFBR2 | P37173 | 1/20 | 0.40 |
| ▸ | PTGES | O14684 | 3/20 | 0.37 |
| ▸ | TNKS | O95271 | 1/20 | 0.37 |
| ▸ | DHODH | Q02127 | 1/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.36 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28689740 | 1.00 | CYP4F2 (0.42) | CYP4F2CYP4A11TGFBR1TGFBR2PTGES | |
| SCHEMBL28689724 | 0.81 | BRD4 (0.48) | NOTUMMAPTMEN1ALDH1A1KMT2A | |
| SCHEMBL29408303 | 0.76 | PIN1 (0.47) | TGFBR1TGFBR2PTGESDHODHMEN1 | |
| SCHEMBL28708977 | 0.76 | PIN1 (0.47) | TGFBR1TGFBR2PTGESDHODHMEN1 | |
| SCHEMBL22678379 | 0.75 | MEN1 (0.42) | MAPTMEN1KMT2A | |
| SCHEMBL29408254 | 0.75 | MEN1 (0.42) | MAPTMEN1KMT2A | |
| SCHEMBL29408212 | 0.74 | BRD4 (0.41) | DHODHALDH1A1TAS2R14 | |
| SCHEMBL28689722 | 0.71 | BRD4 (0.55) | NOTUMTAS2R14 | |
| SCHEMBL38665771 | 0.70 | TAS2R14 (0.43) | MAPTMEN1ALDH1A1KMT2ATEAD4 | |
| SCHEMBL18036035 | 0.70 | PDE2A (0.51) | PTGES |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3969439-A1 | ACSS2 INHIBITORS AND METHODS OF USE THEREOF | Metabomed Ltd (IL) | 2022-03-23 | — | — | EP | disclosed |
| CN-114127049-A | ACSS2 inhibitors and methods of use thereof | 美特波米德有限公司 | 2022-03-01 | — | — | CN | disclosed |