Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 6/20 | 0.39 |
| ▸ | EPAS1 | Q99814 | 2/20 | 0.39 |
| ▸ | VEGFA | P15692 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | TTR | P02766 | 1/20 | 0.38 |
| ▸ | ALB | P02768 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.36 |
| ▸ | ESRRA | P11474 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22658071 | 1.00 | NR3C1 (0.39) | NR3C1EPAS1VEGFAFFAR1MEN1 | |
| SCHEMBL23148790 | 0.86 | SLC22A12 (0.36) | EPAS1VEGFAMEN1TTRALB | |
| SCHEMBL10164859 | 0.83 | SLC22A12 (0.43) | SLC22A12AR | |
| SCHEMBL1963234 | 0.82 | NR3C1 (0.42) | NR3C1FFAR1MEN1TTRALB | |
| SCHEMBL16951654 | 0.82 | ALDH1A1 (0.31) | — | |
| SCHEMBL2448493 | 0.80 | USP30 (0.41) | SLC22A12CYP11B1CYP11B2AR | |
| SCHEMBL12619038 | 0.79 | NR3C1 (0.45) | NR3C1EPAS1FFAR1 | |
| SCHEMBL16955678 | 0.79 | SLC22A12 (0.36) | SLC22A12CYP11B1CYP11B2AR | |
| SCHEMBL16177839 | 0.79 | CA12 (0.38) | SLC22A12CYP11B1CYP11B2AR | |
| SCHEMBL14150477 | 0.79 | KDM4E (0.39) | SLC22A12AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114127049-A | ACSS2 inhibitors and methods of use thereof | 美特波米德有限公司 | 2022-03-01 | — | — | CN | disclosed |