SCHEMBL29408359

SCHEMBL29408359

N[C@@H](CCC(=O)O)C(=O)N1C[C@H](O)C[C@H]1C(=O)NCC(=O)N[C@@H](CCC(=O)O)C(=O)O

nearest known ligand 0.49

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 4/20 0.49
DPP8 Q6V1X1 4/20 0.49
DPP9 Q86TI2 4/20 0.49
KEAP1 Q14145 3/20 0.40
OPRD1 P41143 1/20 0.37
POLB P06746 1/20 0.37
FAP Q12884 1/20 0.37
DPP7 Q9UHL4 1/20 0.37
FOLH1 Q04609 3/20 0.37
RIMKLA Q8IXN7 1/20 0.36
NAALAD2 Q9Y3Q0 1/20 0.36
BDKRB2 P30411 1/20 0.36
OPRM1 P35372 2/20 0.35
EPHX2 P34913 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29408362 0.89 DPP4 (0.40) DPP4DPP8DPP9KEAP1OPRD1
SCHEMBL29391662 0.86 DPP4 (0.57) DPP4DPP8DPP9FAPDPP7
SCHEMBL29485657 0.84 KEAP1 (0.43) KEAP1FOLH1
SCHEMBL29485611 0.82 KEAP1 (0.47) KEAP1FOLH1
SCHEMBL29408364 0.81 KEAP1 (0.39) DPP4DPP8DPP9KEAP1
SCHEMBL30292635 0.81 KEAP1 (0.41) DPP4DPP8DPP9KEAP1BDKRB2
SCHEMBL29408358 0.81 MEN1 (0.39) DPP4DPP8DPP9KEAP1BDKRB2
SCHEMBL32689886 0.78 KEAP1 (0.46) DPP4DPP8DPP9KEAP1OPRD1
SCHEMBL31540102 0.76 DPP4 (0.66) DPP4DPP8DPP9FAPDPP7
SCHEMBL29396034 0.76 DPP4 (0.66) DPP4DPP8DPP9FAPDPP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111647043-B Oligopeptide with platelet resisting and antithrombotic functions containing Hyp-Gly sequence 中国农业大学 2022-03-22 CN claimed
CN-111647043-B Oligopeptide with platelet resisting and antithrombotic functions containing Hyp-Gly sequence 中国农业大学 2022-03-22 CN disclosed