Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 11/20 | 0.43 |
| ▸ | FOLH1 | Q04609 | 4/20 | 0.42 |
| ▸ | VHL | P40337 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29485652 | 0.94 | KEAP1 (0.48) | KEAP1FOLH1VHL | |
| SCHEMBL29485611 | 0.93 | KEAP1 (0.47) | KEAP1FOLH1VHL | |
| SCHEMBL30358533 | 0.91 | KEAP1 (0.48) | KEAP1 | |
| SCHEMBL30358543 | 0.88 | KEAP1 (0.47) | KEAP1 | |
| SCHEMBL29485620 | 0.86 | KEAP1 (0.39) | KEAP1FOLH1VHL | |
| SCHEMBL30358547 | 0.85 | KEAP1 (0.47) | KEAP1 | |
| SCHEMBL29408364 | 0.85 | KEAP1 (0.39) | KEAP1VHL | |
| SCHEMBL29408359 | 0.84 | DPP4 (0.49) | KEAP1FOLH1 | |
| SCHEMBL30862233 | 0.80 | ATM (0.49) | VHL | |
| SCHEMBL30358539 | 0.80 | KEAP1 (0.42) | KEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12454551-B2 | Peptides as inhibitors of fibrotic matrix accumulation | MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN E.V. (DE) | 2025-10-28 | — | — | US | disclosed |
| CN-114364691-B | Peptides as inhibitors of fibrotic matrix accumulation | 马克斯·普朗克科学促进学会 | 2023-12-12 | — | — | CN | disclosed |
| US-20220267378-A1 | PEPTIDES AS INHIBITORS OF FIBROTIC MATRIX ACCUMULATION | MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN E.V. (DE) | 2022-08-25 | — | — | US | disclosed |
| EP-3996694-A1 | PEPTIDES AS INHIBITORS OF FIBROTIC MATRIX ACCUMULATION | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2022-05-18 | — | — | EP | disclosed |
| CN-114364691-A | Peptides as inhibitors of fibrotic matrix accumulation | 马克斯·普朗克科学促进学会 | 2022-04-15 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12454551-B2 | Peptides as inhibitors of fibrotic matrix accumulation | GLS, AGXT, FN1 | KEAP1 1762/4885FOLH1 3178/4885VHL 2977/4885 |
| US-20220267378-A1 | PEPTIDES AS INHIBITORS OF FIBROTIC MATRIX ACCUMULATION | INHA, GLS, AGXT | KEAP1 2478/4885FOLH1 1156/4885VHL 2016/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.