SCHEMBL29408385

SCHEMBL29408385

Fc1ccc2nc3ccc(Cl)cc3n2c1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 4/20 0.58
ALDH1A1 P00352 3/20 0.58
KDM4E B2RXH2 3/20 0.58
GLA P06280 2/20 0.58
POLB P06746 2/20 0.58
HPGD P15428 2/20 0.58
NPSR1 Q6W5P4 1/20 0.58
HSD17B10 Q99714 1/20 0.58
PTPN1 P18031 1/20 0.44
RXFP1 Q9HBX9 1/20 0.41
PDE2A O00408 1/20 0.40
PDE10A Q9Y233 1/20 0.40
RAB9A P51151 4/20 0.40
MAPT P10636 3/20 0.40
MEN1 O00255 3/20 0.40
KMT2A Q03164 3/20 0.40
LMNA P02545 1/20 0.40
NPC1 O15118 3/20 0.38
CASP3 P42574 1/20 0.38
SENP8 Q96LD8 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29408388 0.81 MAPT (0.59) GAAALDH1A1KDM4EPOLBRXFP1
SCHEMBL29408375 0.77 CYP11B1 (0.41) GAAALDH1A1PDE2APDE10AMAPT
SCHEMBL29408374 0.77 CYP11B1 (0.48) GAAALDH1A1KDM4EPOLBHPGD
SCHEMBL8969480 0.69 HTR6 (0.39) GAAALDH1A1KDM4EGLAPOLB
SCHEMBL15175417 0.67 GRIN1 (0.40) ALDH1A1KDM4EPOLBRXFP1RAB9A
SCHEMBL14809711 0.66 CYP11B1 (0.50) SMN1; SMN2CYP11B1CYP11B2
SCHEMBL14810130 0.66 CYP11B2 (0.38) SMN1; SMN2CYP11B1CYP11B2GABRDGABRB1
SCHEMBL14632164 0.66 SLC2A3 (0.46) GAAALDH1A1KDM4EMAPTMEN1
SCHEMBL17582837 0.66 GSR (0.45) GAAALDH1A1KDM4EGLAPOLB
SCHEMBL22615061 0.66 SLC2A3 (0.46) GAAALDH1A1KDM4EMAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111206260-B Electrochemical synthesis method of pyrido [1,2-a ] benzimidazole compound 齐鲁工业大学 2022-03-22 CN disclosed