Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 6/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.39 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.39 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.37 |
| ▸ | CPB2 | Q96IY4 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CPB1 | P15086 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10937318 | 0.95 | ITGB3 (0.44) | ITGB3ITGA2BSLC6A5SLC15A2CPB2 | |
| SCHEMBL541261 | 0.95 | ITGB3 (0.44) | ITGB3ITGA2BSLC6A5SLC15A2CPB2 | |
| SCHEMBL26126284 | 0.95 | ITGB3 (0.44) | ITGB3ITGA2BSLC6A5SLC15A2CPB2 | |
| SCHEMBL7893552 | 0.93 | ITGB3 (0.47) | ITGB3ITGA2BHDAC6SLC6A5SLC15A2 | |
| SCHEMBL7257726 | 0.92 | ITGB3 (0.48) | ITGB3ITGA2BHDAC6SLC6A5SLC15A2 | |
| SCHEMBL7887537 | 0.91 | ITGB3 (0.50) | ITGB3ITGA2BHDAC6HDAC1SLC6A5 | |
| SCHEMBL4653518 | 0.91 | ITGB3 (0.50) | ITGB3ITGA2BHDAC6HDAC1SLC6A5 | |
| SCHEMBL8630043 | 0.91 | ITGB3 (0.50) | ITGB3ITGA2BHDAC6HDAC1SLC6A5 | |
| Carnosine SCHEMBL1161010 | 0.88 | ITGB3 (0.41) | ITGB3ITGA2BSLC6A5SLC15A2CPB2 | |
| Carnosine SCHEMBL33769 | 0.88 | ITGB3 (0.41) | ITGB3ITGA2BSLC6A5SLC15A2CPB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2229935-A1 | Peptide derivatives or pharmaceutically acceptable salts thereof, method for producing the same, use of said derivatives and pharmaceutical composition | Nebolsin, Vladimir Evgenievich (RU) | 2010-09-22 | — | — | EP | disclosed |