SCHEMBL10937318

SCHEMBL10937318

NCCCC(=O)NC(Cc1c[nH]cn1)C(=O)O

nearest known ligand 0.44

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ ITGB3 P05106 8/20 0.44
▸ ITGA2B P08514 8/20 0.44
▸ SLC15A2 Q16348 1/20 0.39
▸ SLC6A5 Q9Y345 2/20 0.39
▸ CPB2 Q96IY4 4/20 0.37
▸ PIN1 Q13526 1/20 0.37
▸ EPHX2 P34913 1/20 0.36
▸ CPB1 P15086 1/20 0.36
▸ PPARG P37231 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26126284 1.00 ITGB3 (0.44) ITGB3ITGA2BSLC15A2SLC6A5CPB2
SCHEMBL541261 1.00 ITGB3 (0.44) ITGB3ITGA2BSLC15A2SLC6A5CPB2
SCHEMBL7893552 0.97 ITGB3 (0.47) ITGB3ITGA2BSLC15A2SLC6A5CPB2
SCHEMBL7257726 0.96 ITGB3 (0.48) ITGB3ITGA2BSLC15A2SLC6A5CPB2
Methoxymethane SCHEMBL2940968 0.95 ITGB3 (0.46) ITGB3ITGA2BSLC15A2SLC6A5CPB2
SCHEMBL7887537 0.95 ITGB3 (0.50) ITGB3ITGA2BSLC15A2SLC6A5
SCHEMBL4653518 0.95 ITGB3 (0.50) ITGB3ITGA2BSLC15A2SLC6A5
SCHEMBL8630043 0.95 ITGB3 (0.50) ITGB3ITGA2BSLC15A2SLC6A5
Carnosine SCHEMBL33768 0.92 ITGB3 (0.41) ITGB3ITGA2BSLC15A2SLC6A5CPB2
Carnosine SCHEMBL3904964 0.92 ITGB3 (0.41) ITGB3ITGA2BSLC15A2SLC6A5CPB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3328409-B1 COMPOSITION FOR THE INCREASE OF HUMORAL SECRETION METIS HEALTHCARE S R L (IT) 2023-08-23 — — EP claimed
WO-2023139414-A1 COMPOSITION FOR TREATING ESOPHAGEAL REFLUX METIS HEALTHCARE S.R.L. (IT) 2023-07-27 — — WO claimed
US-10646476-B2 Method for treatment of humoral secretion dysfunctions METIS HEALTHCARE S.R.L. (IT) 2020-05-12 — — US claimed
US-20180207134-A1 COMPOSITION FOR THE INCREASE OF HUMORAL SECRETION METIS HEALTHCARE S.R.L. (IT) 2018-07-26 — — US claimed
EP-4469034-A1 COMPOSITION FOR TREATING ESOPHAGEAL REFLUX Metis Healthcare S.r.L. (IT) 2024-12-04 — — EP disclosed
US-12083204-B2 Topical composition for homeostatic delivery of nitric oxide and uses thereof L'OREAL (FR) 2024-09-10 — — US disclosed
WO-2023233383-A2 TOPICAL COMPOSITION FOR HOMEOSTATIC DELIVERY OF NITRIC OXIDE AND USES THEREOF L'OREAL (FR) 2023-12-07 — — WO disclosed
US-20230390172-A1 TOPICAL COMPOSITION FOR HOMEOSTATIC DELIVERY OF NITRIC OXIDE AND USES THEREOF Dermaforce Holdings, LLC 2023-12-07 — — US disclosed
WO-2023188173-A1 AGENT FOR INCREASING INTRACEREBRAL GABA 日本ハム株式会社 2023-10-05 — — WO disclosed
EP-3328409-B1 COMPOSITION FOR THE INCREASE OF HUMORAL SECRETION METIS HEALTHCARE S R L (IT) 2023-08-23 — — EP disclosed
WO-2023139414-A1 COMPOSITION FOR TREATING ESOPHAGEAL REFLUX METIS HEALTHCARE S.R.L. (IT) 2023-07-27 — — WO disclosed
CN-115024997-A Cosmetic composition with skin aging resisting effect 彭氏(惠州)实业发展有限公司 2022-09-09 — — CN disclosed
EP-3118211-A1 AMIDE COMPOUNDS AND METHODS FOR THE PRODUCTION AND USE THEREOF Obschestvo S Ogranichennoi Otvetstennostiyu "Pharmenterprises" (RU) 2017-01-18 — — EP disclosed
US-20160271109-A1 Peptides For Skin Rejuvenation And Methods Of Using The Same ANTEIS SA (CH) 2016-09-22 — — US disclosed
US-9375398-B2 Peptides for skin rejuvenation and methods of using the same NEOCUTIS S.A. (CH) 2016-06-28 — — US disclosed
EP-2970382-A2 PEPTIDES FOR SKIN REJUVENATION AND METHODS OF USING THE SAME Neocutis SA (CH) 2016-01-20 — — EP disclosed
CN-102448992-B Stabilizing composition for immobilized biomolecules LEUKOCARE AG 2015-06-10 — — CN disclosed
US-20140309173-A1 Peptides For Skin Rejuvenation And Methods Of Using The Same ANTEIS SA (CH) 2014-10-16 — — US disclosed
WO-2014140890-A2 PEPTIDES FOR SKIN REJUVENATION AND METHODS OF USING THE SAME NEOCUTIS SA (CH) 2014-09-18 — — WO disclosed
US-4529602-A Sulfodehydroabietic acid compound TANABE SEIYAKU CO., LTD. (JP) 1985-07-16 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160271109-A1 Peptides For Skin Rejuvenation And Methods Of Using The Same CUTA, PLOD3, MMP13 ITGB3 3504/4885ITGA2B 3943/4885SLC15A2 1358/4885
US-20140309173-A1 Peptides For Skin Rejuvenation And Methods Of Using The Same CUTA, PLOD3, MMP13 ITGB3 3504/4885ITGA2B 3943/4885SLC15A2 1358/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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