Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.98 |
| ▸ | MAPT | P10636 | 3/20 | 0.89 |
| ▸ | NSD2 | O96028 | 2/20 | 0.89 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.89 |
| ▸ | HTT | P42858 | 2/20 | 0.89 |
| ▸ | RAB9A | P51151 | 2/20 | 0.89 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.89 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.89 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.89 |
| ▸ | NPC1 | O15118 | 1/20 | 0.89 |
| ▸ | THRB | P10828 | 1/20 | 0.89 |
| ▸ | PKM | P14618 | 1/20 | 0.89 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.89 |
| ▸ | INSR | P06213 | 16/20 | 0.84 |
| ▸ | POLB | P06746 | 1/20 | 0.65 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17026626 | 1.00 | APP (0.98) | APPMAPTNSD2MAPK1HTT | |
| SCHEMBL17026625 | 1.00 | APP (0.98) | APPMAPTNSD2MAPK1HTT | |
| SCHEMBL2442132 | 0.99 | APP (1.00) | APPMAPTNSD2MAPK1HTT | |
| SCHEMBL2442135 | 0.99 | APP (1.00) | APPMAPTNSD2MAPK1HTT | |
| Perchlorate SCHEMBL10380076 | 0.95 | MAPT (0.98) | APPMAPTNSD2MAPK1HTT | |
| Perchlorate SCHEMBL74803 | 0.94 | MAPT (1.00) | APPMAPTNSD2MAPK1HTT | |
| Perchlorate SCHEMBL29431897 | 0.94 | MAPT (1.00) | APPMAPTNSD2MAPK1HTT | |
| Perchlorate SCHEMBL74804 | 0.94 | MAPT (1.00) | APPMAPTNSD2MAPK1HTT | |
| Perchlorate SCHEMBL29454358 | 0.94 | MAPT (1.00) | APPMAPTNSD2MAPK1HTT | |
| SCHEMBL9580682 | 0.91 | INSR (1.00) | APPMAPTNSD2MAPK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250340547-A1 | NOVEL COMPOUNDS FOR IMAGING TAU PROTEINS THAT ACCUMULATE IN THE BRAIN | NATIONAL INSTITUTES FOR QUANTUM AND RADIOLOGICAL SCIENCE AND TECHNOLOGY (JP) | 2025-11-06 | — | — | US | disclosed |
| US-12195454-B2 | Compounds for imaging tau proteins that accumulate in the brain | NATIONAL INSTITUTES FOR QUANTUM AND RADIOLOGICAL SCIENCE AND TECHNOLOGY (JP) | 2025-01-14 | — | — | US | disclosed |
| US-20240083893-A1 | COMPOUNDS FOR IMAGING TAU PROTEINS THAT ACCUMULATE IN THE BRAIN | NATIONAL INSTITUTES FOR QUANTUM AND RADIOLOGICAL SCIENCE AND TECHNOLOGY (JP) | 2024-03-14 | — | — | US | disclosed |
| US-11667628-B2 | Compounds for imaging tau proteins that accumulate in brain | NATIONAL INSTITUTES FOR QUANTUM AND RADIOLOGICAL SCIENCE AND TECHNOLOGY (JP) | 2023-06-06 | — | — | US | disclosed |
| US-20220056020-A1 | NOVEL COMPOUNDS FOR IMAGING TAU PROTEINS THAT ACCUMULATE IN BRAIN | NATIONAL INSTITUTES FOR QUANTUM AND RADIOLOGICAL SCIENCE AND TECHNOLOGY (JP) | 2022-02-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240083893-A1 | COMPOUNDS FOR IMAGING TAU PROTEINS THAT ACCUMULATE IN THE BRAIN | MAPT, FABP7, HTT | APP 24/4885MAPT 1/4885NSD2 4337/4885 |
| US-12195454-B2 | Compounds for imaging tau proteins that accumulate in the brain | MAPT, FABP7, HTT | APP 24/4885MAPT 1/4885NSD2 4337/4885 |
| US-11667628-B2 | Compounds for imaging tau proteins that accumulate in brain | MAPT, FABP7, HTT | APP 17/4885MAPT 1/4885NSD2 4288/4885 |
| US-20220056020-A1 | NOVEL COMPOUNDS FOR IMAGING TAU PROTEINS THAT ACCUMULATE IN BRAIN | MAPT, FABP7, HTT | APP 24/4885MAPT 1/4885NSD2 4351/4885 |
| US-20250340547-A1 | NOVEL COMPOUNDS FOR IMAGING TAU PROTEINS THAT ACCUMULATE IN THE BRAIN | MAPT, FABP7, HTT | APP 21/4885MAPT 1/4885NSD2 4474/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.