SCHEMBL9580682

SCHEMBL9580682

CC[n+]1c(/C=C/c2ccc(N(C)C)cc2)sc2ccccc21

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
INSR P06213 18/20 1.00
APP P05067 1/20 0.86
NPC1 O15118 1/20 0.78
NSD2 O96028 1/20 0.78
MAPT P10636 1/20 0.78
THRB P10828 1/20 0.78
PKM P14618 1/20 0.78
MAPK1 P28482 1/20 0.78
HTT P42858 1/20 0.78
RAB9A P51151 1/20 0.78
KMT2A Q03164 1/20 0.78
NPSR1 Q6W5P4 1/20 0.78
RXFP1 Q9HBX9 1/20 0.78
L3MBTL1 Q9Y468 1/20 0.78

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9580683 1.00 INSR (1.00) INSRAPPNPC1NSD2MAPT
Iodide SCHEMBL7028400 0.99 INSR (0.97) INSRAPPNPC1NSD2MAPT
Iodide SCHEMBL29757617 0.99 INSR (0.97) INSRAPPNPC1NSD2MAPT
Bromide SCHEMBL22598035 0.99 INSR (0.97) INSRAPPNPC1NSD2MAPT
Bromide SCHEMBL22598036 0.99 INSR (0.97) INSRAPPNPC1NSD2MAPT
Iodide SCHEMBL5679445 0.99 INSR (0.97) INSRAPPNPC1NSD2MAPT
SCHEMBL2442132 0.92 APP (1.00) INSRAPPNPC1NSD2MAPT
SCHEMBL2442135 0.92 APP (1.00) INSRAPPNPC1NSD2MAPT
SCHEMBL17026626 0.91 APP (0.98) INSRAPPNPC1NSD2MAPT
SCHEMBL29409742 0.91 APP (0.98) INSRAPPNPC1NSD2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11215559-B2 Thallium doped gadolinium chalcogenide nanocomposite KING ABDULAZIZ UNIVERSITY (SA) 2022-01-04 US disclosed
US-11209365-B1 Thallium-gadolinium-chalcogenide nanodot composition KING ABDULAZIZ UNIVERSITY (SA) 2021-12-28 US disclosed
US-11209366-B1 Quantum dot nanocomposite containing benzothiazolium KING ABDULAZIZ UNIVERSITY (SA) 2021-12-28 US disclosed
US-20210381974-A1 QUANTUM DOT NANOCOMPOSITE CONTAINING BENZOTHIAZOLIUM KING ABDULAZIZ UNIVERSITY (SA) 2021-12-09 US disclosed
US-20210381973-A1 THALLIUM-GADOLINIUM-YTTRIUM NANODOT COMPOSITION KING ABDULAZIZ UNIVERSITY (SA) 2021-12-09 US disclosed
US-20210341388-A1 THALLIUM DOPED GADOLINIUM CHALCOGENIDE NANOCOMPOSITE KING ABDULAZIZ UNIVERSITY (SA) 2021-11-04 US disclosed
US-11143592-B2 Method of detecting antimony ions and method of removing antimony ions using a fluorescent nanocomposite KING ABDULAZIZ UNIVERSITY (SA) 2021-10-12 US disclosed
US-20210054269-A1 FLUORESCENT NANOCOMPOSITE AND A METHOD OF DETECTING ANTIMONY IONS KING ABDULAZIZ UNIVERSITY (SA) 2021-02-25 US disclosed
US-10823674-B1 Antimony adsorbent KING ABDULAZIZ UNIVERSITY (SA) 2020-11-03 US disclosed
US-20120035187-A1 ANTI-NEURODEGENERATIVE DISEASE AGENT KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) 2012-02-09 US disclosed
US-5242892-A With 5-aminolevulinic acid THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 1993-09-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120035187-A1 ANTI-NEURODEGENERATIVE DISEASE AGENT SNCA, PSEN1, CDR2 INSR 3376/4885APP 15/4885NPC1 151/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.