SCHEMBL294098

SCHEMBL294098

COCCO[Si](C)(C)C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL892809 0.91 CA2 (0.34)
SCHEMBL4302198 0.91 CA2 (0.34)
SCHEMBL1223591 0.86
SCHEMBL4434977 0.81 ALDH1A1 (0.32)
SCHEMBL600689 0.80
SCHEMBL221636 0.80
SCHEMBL14448692 0.79 ALDH1A1 (0.41)
SCHEMBL14448693 0.79 ALDH1A1 (0.41)
SCHEMBL17154155 0.79 ALDH1A1 (0.41)
SCHEMBL10014107 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 126 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004037827-A1 SYNTHESIS OF SPIRO ORTHO ESTERS, SPIRO ORTHO CARBONATES, AND INTERMEDIATES BIOAVAILABILITY SYSTEMS, LLC (US) 2004-05-06 WO claimed
US-20040002611-A1 Synthesis of spiro esters, spiro ortho carbonates, and intermediates BIOAVAILABILITY SYSTEMS, LLC (US) 2004-01-01 US claimed
US-6613918-B1 Reacting an ester or carbonate with a tri C1-20 alkyl oxonium hexafluorophosphate; Bergaptols BIOAVAILABILITY SYSTEMS, LLC 2003-09-02 US claimed
EP-0376870-A1 A new organosilylpolyphosphoric reagent, its preparation and application to the process of synthesis of 3-carboxyquinolones or azaquinolones and their salts CENTRO MARGA PARA LA INVESTIGACION S.A. (ES) 1990-07-04 EP claimed
EP-3429980-B1 SURFACE APPLIED CORROSION INHIBITOR SIKA TECH AG (CH) 2026-05-13 EP disclosed
CN-109071366-B Surface applied corrosion inhibitor 建筑研究和技术有限公司 2022-05-10 CN disclosed
US-20210214564-A1 SURFACE APPLIED CORROSION INHIBITOR SIKA TECHNOLOGY AG (CH) 2021-07-15 US disclosed
EP-3842382-A1 PREPARATION OF FLUOROSULFONATE ONIUM SALTS Trinapco, Inc (US) 2021-06-30 EP disclosed
US-11001716-B2 Surface applied corrosion inhibitor CONSTRUCTION RESEARCH & TECHNOLOGY GMBH (DE) 2021-05-11 US disclosed
EP-2953929-B1 PREPARATION OF FLUOROSULFONATE ONIUM SALTS TRINAPCO INC (US) 2021-04-14 EP disclosed
EP-3708163-A1 USE OF SPARSENTAN FOR THE TREATMENT OF CHRONIC INFLAMMATORY DISEASES Ligand Pharmaceuticals, Inc. (US) 2020-09-16 EP disclosed
EP-3222277-B1 A BIPHENYLSULFONAMIDE ENDOTHELIN AND ANGIOTENSIN II RECEPTOR ANTAGONIST TO TREAT GLOMERULOSCLEROSIS AND IGA-INDUCED NEPHROPATHY LIGAND PHARM INC (US) 2020-02-26 EP disclosed
WO-2000058373-A1 PROCESS FOR PRODUCING POLYOLEFINS EASTMAN CHEMICAL COMPANY (US) 2000-10-05 WO disclosed
WO-2000058372-A1 PROCESS FOR PRODUCING POLYOLEFINS EASTMAN CHEMICAL COMPANY (US) 2000-10-05 WO disclosed
WO-2000058371-A1 PROCESS FOR PRODUCING POLYOLEFINS EASTMAN CHEMICAL COMPANY (US) 2000-10-05 WO disclosed
WO-2000052069-A1 PROCESS FOR PRODUCING POLYETHYLENE EASTMAN CHEMICAL COMPANY (US) 2000-09-08 WO disclosed
WO-2000052068-A1 PROCESS FOR PRODUCING POLYETHYLENE EASTMAN CHEMICAL COMPANY (US) 2000-09-08 WO disclosed
WO-2000052067-A1 PROCESS FOR PRODUCING POLYETHYLENE EASTMAN CHEMICAL COMPANY (US) 2000-09-08 WO disclosed
WO-2000001389-A1 BIPHENYL SULFONAMIDES AS DUAL ANGIOTENSIN ENDOTHELIN RECEPTOR ANTAGONISTS BRISTOL-MYERS SQUIBB CO. (US) 2000-01-13 WO disclosed
EP-0553673-A1 N,N-bis-(2-chloroethyl)phosphoric acid diamidates as cytostatics Tietze, Lutz F., Prof. Dr. (DE) 1993-08-04 EP disclosed