Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | XBP1 | P17861 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22658194 | 1.00 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2TP53ACSS2MAPT | |
| SCHEMBL22658193 | 1.00 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2TP53ACSS2MAPT | |
| SCHEMBL24027994 | 0.87 | ALDH1A1 (0.58) | ALDH1A1SMN1; SMN2TP53MAPTMEN1 | |
| SCHEMBL24028391 | 0.87 | ALDH1A1 (0.58) | ALDH1A1SMN1; SMN2TP53MAPTMEN1 | |
| SCHEMBL29409971 | 0.86 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2TP53ACSS2MAPT | |
| SCHEMBL22678605 | 0.86 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2TP53ACSS2MAPT | |
| SCHEMBL24028135 | 0.81 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2TP53MAPTMEN1 | |
| SCHEMBL30213098 | 0.81 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2TP53MAPTMEN1 | |
| SCHEMBL24027845 | 0.80 | LMNA (0.46) | ALDH1A1SMN1; SMN2TP53MAPTMEN1 | |
| SCHEMBL30255658 | 0.80 | LMNA (0.46) | ALDH1A1SMN1; SMN2TP53MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3969439-A1 | ACSS2 INHIBITORS AND METHODS OF USE THEREOF | Metabomed Ltd (IL) | 2022-03-23 | — | — | EP | disclosed |