Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 2/20 | 1.00 |
| ▸ | CACNA1C | Q13936 | 10/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.59 |
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.59 |
| ▸ | TSHR | P16473 | 3/20 | 0.59 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.59 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.59 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.59 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.59 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.59 |
| ▸ | PGR | P06401 | 1/20 | 0.59 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.59 |
| ▸ | HTR1A | P08908 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Efonidipine SCHEMBL49637 | 1.00 | ABCB1 (1.00) | ABCB1CACNA1CCYP1A2CYP3A4CYP2D6 | |
| Efonidipine SCHEMBL29379054 | 1.00 | ABCB1 (1.00) | ABCB1CACNA1CCYP1A2CYP3A4CYP2D6 | |
| Efonidipine SCHEMBL49638 | 1.00 | ABCB1 (1.00) | ABCB1CACNA1CCYP1A2CYP3A4CYP2D6 | |
| Efonidipine SCHEMBL349046 | 0.99 | ABCB1 (0.99) | ABCB1CACNA1CCYP1A2CYP3A4CYP2D6 | |
| Efonidipine SCHEMBL332377 | 0.99 | ABCB1 (0.99) | ABCB1CACNA1CCYP1A2CYP3A4CYP2D6 | |
| Efonidipine SCHEMBL678571 | 0.99 | ABCB1 (0.97) | ABCB1CACNA1CCYP1A2CYP3A4CYP2D6 | |
| Efonidipine SCHEMBL28844127 | 0.99 | ABCB1 (0.97) | ABCB1CACNA1CCYP1A2CYP3A4CYP2D6 | |
| Efonidipine SCHEMBL27650540 | 0.98 | ABCB1 (0.96) | ABCB1CACNA1CCYP1A2CYP3A4CYP2D6 | |
| Efonidipine SCHEMBL909287 | 0.97 | ABCB1 (0.95) | ABCB1CACNA1CCYP1A2CYP3A4CYP2D6 | |
| Efonidipine SCHEMBL909286 | 0.97 | ABCB1 (0.95) | ABCB1CACNA1CCYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3615010-B1 | METHODS FOR TREATING DRAVET SYNDROME | CAVION INC (US) | 2024-08-21 | — | — | EP | disclosed |
| CN-110770221-B | Methods for improving memory and cognition and for treating memory and cognition disorders | 卡维昂公司 | 2023-09-08 | — | — | CN | disclosed |
| EP-3364993-B1 | METHODS FOR TREATING ANGELMAN SYNDROME | CAVION INC (US) | 2022-11-09 | — | — | EP | disclosed |
| US-11324733-B2 | Methods for improving memory and cognition and for treating memory and cognitive disorders | CAVION, INC. (US) | 2022-05-10 | — | — | US | disclosed |
| US-11273218-B2 | Methods for treating Angelman syndrome and related disorders | CAVION, INC. (US) | 2022-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11273218-B2 | Methods for treating Angelman syndrome and related disorders | CACNA1G, CACNA1I, CACNA1H | ABCB1 1948/4885CACNA1C 16/4885CYP1A2 4539/4885 |
| US-11324733-B2 | Methods for improving memory and cognition and for treating memory and cognitive disorders | CACNA1G, CACNA1I, CACNA1H | ABCB1 3075/4885CACNA1C 8/4885CYP1A2 4356/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.