Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | KIF11 | P52732 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | LTA4H | P09960 | 1/20 | 0.47 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28717992 | 1.00 | MAPT (0.56) | MAPTPOLBTDP1ALDH1A1KIF11 | |
| SCHEMBL12997448 | 0.86 | SPHK1 (0.60) | MAPTPOLBTDP1ALDH1A1KIF11 | |
| SCHEMBL12892347 | 0.86 | ALDH1A1 (0.58) | MAPTPOLBTDP1ALDH1A1KIF11 | |
| SCHEMBL6518397 | 0.83 | AAK1 (0.67) | MAPTPOLBAAK1 | |
| SCHEMBL26464924 | 0.83 | S1PR1 (0.59) | MAPTPOLBTDP1ALDH1A1KIF11 | |
| SCHEMBL26464130 | 0.82 | LTA4H (0.60) | MAPTPOLBALDH1A1LTA4HSPHK1 | |
| SCHEMBL17368403 | 0.82 | MAPT (0.61) | MAPTPOLBTDP1ALDH1A1KIF11 | |
| SCHEMBL29410398 | 0.82 | NPC1 (0.53) | MAPTPOLBALDH1A1NPC1CA12 | |
| SCHEMBL29410393 | 0.82 | ALDH1A1 (0.53) | MAPTPOLBALDH1A1NPC1RAB9A | |
| SCHEMBL28716712 | 0.82 | NPC1 (0.53) | MAPTPOLBALDH1A1NPC1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110903341-B | Progesterone-pyrazine amide compound, preparation method and anticancer application thereof | 西北农林科技大学 | 2022-03-15 | — | — | CN | disclosed |