Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 11/20 | 0.52 |
| ▸ | CDC25B | P30305 | 8/20 | 0.52 |
| ▸ | TACR2 | P21452 | 2/20 | 0.51 |
| ▸ | PTPN2 | P17706 | 6/20 | 0.51 |
| ▸ | PTPN11 | Q06124 | 5/20 | 0.51 |
| ▸ | PTPN6 | P29350 | 4/20 | 0.51 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.50 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.50 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.50 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.50 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.50 |
| ▸ | NT5E | P21589 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26349703 | 0.91 | TACR2 (0.45) | PTPN1CDC25BTACR2PTPN2PTPN11 | |
| SCHEMBL29410628 | 0.86 | PTPN1 (0.56) | PTPN1CDC25BPTPN2PTPN11PTPN6 | |
| SCHEMBL18405449 | 0.83 | TACR2 (0.58) | PTPN1CDC25BTACR2PTPN2PTPN11 | |
| SCHEMBL38652098 | 0.82 | PTPN1 (0.49) | PTPN1CDC25BTACR2PTPN2PTPN11 | |
| SCHEMBL26354602 | 0.81 | TACR2 (0.46) | TACR2SSTR1SSTR2SSTR4SSTR3 | |
| SCHEMBL23226955 | 0.81 | PTPN1 (0.55) | PTPN1CDC25BTACR2PTPN2PTPN11 | |
| SCHEMBL23220268 | 0.81 | PTPN1 (0.55) | PTPN1CDC25BTACR2PTPN2PTPN11 | |
| SCHEMBL19400292 | 0.81 | SSTR1 (0.58) | PTPN1CDC25BTACR2PTPN2PTPN11 | |
| SCHEMBL977853 | 0.80 | SSTR1 (0.59) | PTPN1CDC25BPTPN2PTPN11PTPN6 | |
| SCHEMBL6544934 | 0.80 | SSTR1 (0.59) | PTPN1CDC25BPTPN2PTPN11PTPN6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4200022-A1 | TRIPTOLIDE CONJUGATES AND USES THEREOF | Reyoung Corporation (US) | 2023-06-28 | — | — | EP | disclosed |
| WO-2022040487-A1 | TRIPTOLIDE CONJUGATES AND USES THEREOF | REYOUNG CORPORATION (US) | 2022-02-24 | — | — | WO | disclosed |