Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.36 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.36 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | CHKA | P35790 | 4/20 | 0.33 |
| ▸ | AHR | P35869 | 3/20 | 0.32 |
| ▸ | TSHR | P16473 | 5/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.31 |
| ▸ | RELA | Q04206 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4523362 | 1.00 | CSNK2A2 (0.36) | CSNK2A2CSNK2BCSNK2A1TP53CHKA | |
| SCHEMBL30489827 | 0.77 | L3MBTL1 (0.38) | HSD17B10ALDH1A1SMN1; SMN2 | |
| SCHEMBL26607249 | 0.77 | VCAM1 (0.39) | — | |
| SCHEMBL2797388 | 0.77 | L3MBTL1 (0.38) | HSD17B10ALDH1A1SMN1; SMN2 | |
| SCHEMBL9796610 | 0.77 | ESR2 (0.41) | CHKAALDH1A1SMN1; SMN2 | |
| SCHEMBL26215514 | 0.76 | CSNK2A2 (0.39) | CSNK2A2CSNK2BCSNK2A1TP53CHKA | |
| SCHEMBL8754565 | 0.76 | CHKA (0.37) | CSNK2A2CSNK2BCSNK2A1TP53CHKA | |
| SCHEMBL2795974 | 0.75 | CYP2A6 (0.44) | TSHRLMNA | |
| Iodide SCHEMBL2551843 | 0.74 | CHKA (0.36) | CSNK2A2CSNK2BCSNK2A1TP53CHKA | |
| SCHEMBL11817663 | 0.74 | CSNK2A2 (0.36) | CSNK2A2CSNK2BCSNK2A1TP53AHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4486734-A1 | QUINOLINE CGAS ANTAGONIST COMPOUNDS | Immunesensor Therapeutics, Inc. (US) | 2025-01-08 | — | — | EP | disclosed |
| CN-119137112-A | Quinoline cGAS antagonist compounds | 免疫传感器治疗股份有限公司 | 2024-12-13 | — | — | CN | disclosed |
| WO-2023168367-A1 | QUINOLINE cGAS ANTAGONIST COMPOUNDS | IMMUNESENSOR THERAPEUTICS, INC. (US) | 2023-09-07 | — | — | WO | disclosed |
| EP-4208452-A1 | QUINOLINE CGAS ANTAGONIST COMPOUNDS | Immunesensor Therapeutics, Inc. (US) | 2023-07-12 | — | — | EP | disclosed |
| WO-2022051634-A1 | QUINOLINE CGAS ANTAGONIST COMPOUNDS | IMMUNESENSOR THERAPEUTICS, INC. (US) | 2022-03-10 | — | — | WO | disclosed |