Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL29411356

CCC(C)C(NC(=O)C(CCC(=O)O)NC(=O)C(CCC(=O)O)NC(=O)C(CC(C)C)NC(=O)C(N)Cc1ccccc1)C(=O)O.N

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ BACE1 P56817 17/20 0.56
▸ BACE2 Q9Y5Z0 4/20 0.56
▸ CTSD P07339 4/20 0.55
▸ REN P00797 1/20 0.51
▸ OPRM1 P35372 1/20 0.49
▸ OPRD1 P41143 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18907573 0.94 BACE1 (0.54) BACE1BACE2CTSD
SCHEMBL30542169 0.92 BACE1 (0.54) BACE1BACE2CTSD
SCHEMBL30051502 0.92 CTSD (0.59) CTSDRENOPRM1OPRD1
SCHEMBL29425531 0.90 BACE1 (0.64) BACE1BACE2CTSD
SCHEMBL29630630 0.89 BACE1 (0.56) BACE1BACE2CTSD
SCHEMBL8364612 0.88 BACE1 (0.63) BACE1BACE2CTSDREN
SCHEMBL29384172 0.88 LTA4H (0.62) BACE1BACE2CTSD
SCHEMBL30904472 0.87 BACE1 (0.56) BACE1BACE2CTSDOPRM1OPRD1
SCHEMBL30903468 0.87 LTA4H (0.63) BACE1BACE2CTSD
SCHEMBL31720977 0.87 LTA4H (0.63) BACE1BACE2CTSD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114401986-B Antibody compositions for disrupting biological membranes 国家儿童医院研究所 2024-11-08 — — CN disclosed
CN-111386284-B Chimeric phagocytic receptor molecules and methods of use 森罗治疗公司 2024-08-30 — — CN disclosed
CN-110139933-B Ataxin expression constructs 英特瑞克斯顿股份有限公司 2024-03-08 — — CN disclosed
US-20230406911-A1 COMPOSITIONS AND METHODS FOR PREVENTING, INHIBITING, DISRUPTING, OR TREATING A POLYMICROBIAL BIOFILM RESEARCH INSTITUTE AT NATIONWIDE CHILDREN'S HOSPITAL (US) 2023-12-21 — — US disclosed
CN-110072885-B TGF beta signal converter 2赛文缇生物公司 2023-12-19 — — CN disclosed
CN-109963586-B Biological fusion proteins as anti-malarial vaccines 维克芙奥私人有限公司 2023-11-03 — — CN disclosed
EP-4237445-A2 COMPOSITIONS AND METHODS FOR PREVENTING, INHIBITING, DISRUPTING, OR TREATING A POLYMICROBIAL BIOFILM Research Institute at Nationwide Children's Hospital (US) 2023-09-06 — — EP disclosed
CN-114350646-B UDP-sugar epimerase PsUGE2 and application thereof in synthesis of arabinoside 北京理工大学 2023-08-29 — — CN disclosed
CN-116490778-A Compositions and methods for preventing, inhibiting, disrupting or treating a multi-microbial biofilm 国家儿童医院研究所 2023-07-25 — — CN disclosed
CN-116235054-A Method for determining a subject's predisposition from a light-medium COVID-19 disease course to a severe or critical disease course 赛欧米克斯股份有限公司 2023-06-06 — — CN disclosed
WO-2023021151-A1 BURDEN-ADDICTED PRODUCTION STRAINS ENDURO GENETICS APS (DK) 2023-02-23 — — WO disclosed
CN-115248317-A Antigen of soybean allergy 朋友股份有限公司 2022-10-28 — — CN disclosed
CN-109234295-B Method for synthesizing fatty alcohol acetate in microorganism body based on fatty acid 赣南师范大学 2022-09-23 — — CN disclosed
CN-109234294-B Method for synthesizing fatty alcohol acetate in microorganism based on fatty acyl-ACP 赣南师范大学 2022-09-23 — — CN disclosed
CN-114981443-A Arenaviruses as vectors 巴塞尔大学 2022-08-30 — — CN disclosed
CN-108700574-B Antigens of soybean allergy 朋友股份有限公司 2022-07-15 — — CN disclosed
CN-114502733-A Flowering phase genes and methods of use thereof 未名生物农业集团有限公司 2022-05-13 — — CN disclosed
WO-2022094433-A2 COMPOSITIONS AND METHODS FOR PREVENTING, INHIBITING, DISRUPTING, OR TREATING A POLYMICROBIAL BIOFILM RESEARCH INSTITUTE AT NATIONWIDE CHILDREN'S HOSPITAL (US) 2022-05-05 — — WO disclosed
CN-114350646-A UDP-sugar epimerase PsUGE2 and application thereof in arabinoside synthesis 北京理工大学 2022-04-15 — — CN disclosed
CN-113721034-B Time-resolved immunochromatography test strip and kit for detecting S100B protein, and preparation method and application thereof 瑞博奥(广州)生物科技股份有限公司 2022-02-25 — — CN disclosed
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