Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.81 |
| ▸ | MAPT | P10636 | 1/20 | 0.81 |
| ▸ | RECQL | P46063 | 1/20 | 0.72 |
| ▸ | POLB | P06746 | 2/20 | 0.65 |
| ▸ | MEN1 | O00255 | 4/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.64 |
| ▸ | PKM | P14618 | 1/20 | 0.63 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.61 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.61 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | GLA | P06280 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28481747 | 1.00 | LMNA (0.81) | LMNAMAPTRECQLPOLBMEN1 | |
| SCHEMBL2361056 | 0.90 | TP53 (0.69) | LMNAMAPTRECQLPOLBMEN1 | |
| SCHEMBL3432866 | 0.90 | LMNA (1.00) | LMNAMAPTRECQLPOLBMEN1 | |
| SCHEMBL28487275 | 0.89 | AGTR1 (0.76) | LMNAMAPTMEN1KMT2AAGTR1 | |
| SCHEMBL29411886 | 0.89 | AGTR1 (0.76) | LMNAMAPTMEN1KMT2AAGTR1 | |
| SCHEMBL29968953 | 0.88 | LMNA (0.67) | LMNAMAPTRECQLPOLBAGTR1 | |
| SCHEMBL28716632 | 0.88 | LMNA (0.67) | LMNAMAPTRECQLPOLBAGTR1 | |
| SCHEMBL29968482 | 0.88 | LMNA (0.67) | LMNAMAPTRECQLPOLBAGTR1 | |
| SCHEMBL28878994 | 0.88 | LMNA (0.67) | LMNAMAPTRECQLPOLBAGTR1 | |
| SCHEMBL28879019 | 0.88 | LMNA (0.67) | LMNAMAPTRECQLPOLBAGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022057930-A1 | BENZIMIDAZOLE COMPOUND HAVING ENDOTHELIAL LIPASE INHIBITION EFFECT, AND APPLICATION | 盐城师范学院 | 2022-03-24 | — | — | WO | disclosed |