Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 9/20 | 0.50 |
| ▸ | PARP1 | P09874 | 4/20 | 0.49 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.47 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.47 |
| ▸ | FBP1 | P09467 | 1/20 | 0.43 |
| ▸ | CASR | P41180 | 1/20 | 0.43 |
| ▸ | CD38 | P28907 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28479697 | 1.00 | PPARG (0.50) | PPARGPARP1PKN1PKN2FBP1 | |
| SCHEMBL28494472 | 0.88 | PARP1 (0.49) | PPARGPARP1PKN1PKN2FBP1 | |
| SCHEMBL28903065 | 0.87 | CASR (0.47) | PPARGPARP1PKN1PKN2CASR | |
| SCHEMBL29412030 | 0.87 | CASR (0.47) | PPARGPARP1PKN1PKN2CASR | |
| SCHEMBL29412017 | 0.85 | PKN1 (0.56) | PARP1PKN1PKN2FBP1 | |
| SCHEMBL28487665 | 0.85 | PKN1 (0.56) | PARP1PKN1PKN2FBP1 | |
| SCHEMBL29412060 | 0.84 | PKN1 (0.54) | PPARGPARP1PKN1PKN2 | |
| SCHEMBL28487660 | 0.83 | TP53 (0.61) | PPARGPARP1PKN1PKN2CD38 | |
| SCHEMBL29412071 | 0.83 | TP53 (0.61) | PPARGPARP1PKN1PKN2CD38 | |
| SCHEMBL28478408 | 0.81 | ALDH1A1 (0.58) | PPARGPARP1PKN1PKN2FBP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022057930-A1 | BENZIMIDAZOLE COMPOUND HAVING ENDOTHELIAL LIPASE INHIBITION EFFECT, AND APPLICATION | 盐城师范学院 | 2022-03-24 | — | — | WO | disclosed |