Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 4/20 | 0.62 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.59 |
| ▸ | PDE6D | O43924 | 1/20 | 0.59 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.59 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.59 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | RHEB | Q15382 | 1/20 | 0.53 |
| ▸ | RORC | P51449 | 2/20 | 0.52 |
| ▸ | BRD4 | O60885 | 6/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29412125 | 0.92 | TP53 (0.72) | TP53MAPTALDH1A1PDE6DALDH2 | |
| SCHEMBL29411888 | 0.91 | TP53 (0.70) | TP53MAPTALDH1A1PDE6DALDH2 | |
| SCHEMBL29412064 | 0.87 | RORC (0.54) | TP53MAPTALDH1A1PDE6DALDH2 | |
| SCHEMBL29412013 | 0.87 | ALDH1A1 (0.73) | TP53MAPTALDH1A1PDE6DALDH2 | |
| SCHEMBL29412114 | 0.85 | RORC (0.48) | TP53MAPTALDH1A1PDE6DALDH2 | |
| SCHEMBL29412068 | 0.85 | ALDH1A1 (0.82) | TP53MAPTALDH1A1PDE6DALDH2 | |
| SCHEMBL24185756 | 0.85 | RORC (0.55) | TP53MAPTALDH1A1PDE6DALDH2 | |
| SCHEMBL31591999 | 0.85 | RORC (0.55) | TP53MAPTALDH1A1PDE6DALDH2 | |
| SCHEMBL29412089 | 0.83 | BRD4 (0.64) | TP53MAPTALDH1A1PDE6DALDH2 | |
| SCHEMBL28903085 | 0.83 | BRD4 (0.64) | TP53MAPTALDH1A1PDE6DALDH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022057930-A1 | BENZIMIDAZOLE COMPOUND HAVING ENDOTHELIAL LIPASE INHIBITION EFFECT, AND APPLICATION | 盐城师范学院 | 2022-03-24 | — | — | WO | disclosed |