Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNASE1L3 | Q13609 | 1/20 | 1.00 |
| ▸ | PRMT1 | Q99873 | 1/20 | 1.00 |
| ▸ | USP2 | O75604 | 3/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | ALPL | P05186 | 1/20 | 0.52 |
| ▸ | ALPI | P09923 | 1/20 | 0.52 |
| ▸ | ALPG | P10696 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 16/20 | 0.51 |
| ▸ | CA1 | P00915 | 14/20 | 0.51 |
| ▸ | CA2 | P00918 | 14/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | PLEC | Q15149 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 5/20 | 0.49 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.47 |
| ▸ | CA7 | P43166 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6037129 | 1.00 | DNASE1L3 (1.00) | DNASE1L3PRMT1USP2L3MBTL1MEN1 | |
| SCHEMBL12842816 | 0.94 | DNASE1L3 (0.88) | DNASE1L3PRMT1USP2L3MBTL1MEN1 | |
| SCHEMBL30563616 | 0.83 | DNASE1L3 (0.71) | DNASE1L3PRMT1USP2L3MBTL1MEN1 | |
| SCHEMBL17243936 | 0.82 | DNASE1L3 (0.70) | DNASE1L3PRMT1USP2L3MBTL1MEN1 | |
| SCHEMBL17974475 | 0.81 | DNASE1L3 (0.68) | DNASE1L3PRMT1USP2L3MBTL1MEN1 | |
| SCHEMBL17974603 | 0.80 | DNASE1L3 (0.66) | DNASE1L3PRMT1USP2L3MBTL1MEN1 | |
| SCHEMBL24454976 | 0.79 | DNASE1L3 (0.65) | DNASE1L3PRMT1USP2L3MBTL1MEN1 | |
| SCHEMBL17971015 | 0.79 | DNASE1L3 (0.65) | DNASE1L3PRMT1USP2L3MBTL1MEN1 | |
| SCHEMBL609275 | 0.79 | DNASE1L3 (0.65) | DNASE1L3PRMT1USP2L3MBTL1MEN1 | |
| 6-Carboxyfluorescein SCHEMBL9906208 | 0.79 | USP2 (0.69) | DNASE1L3PRMT1USP2L3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230332256-A1 | NUCLEIC ACID DETECTION USING A NUCLEASE ACTUATOR | UNIV JOHNS HOPKINS (US) | 2023-10-19 | — | — | US | claimed |
| WO-2022061172-A2 | NUCLEIC ACID DETECTION USING A NUCLEASE ACTUATOR | THE JOHNS HOPKINS UNIVERSITY (US) | 2022-03-24 | — | — | WO | claimed |
| US-20230332256-A1 | NUCLEIC ACID DETECTION USING A NUCLEASE ACTUATOR | UNIV JOHNS HOPKINS (US) | 2023-10-19 | — | — | US | disclosed |
| WO-2022067032-A9 | CANCER THERAPEUTIC COMPOSITIONS AND METHODS TARGETING DNASE1L3 | PROVIDENCE HEALTH & SERVICES - OREGON (US) | 2022-06-23 | — | — | WO | disclosed |
| WO-2022067032-A1 | CANCER THERAPEUTIC COMPOSITIONS AND METHODS TARGETING DNASE1L3 | PROVIDENCE HEALTH & SERVICES - OREGON (US) | 2022-03-31 | — | — | WO | disclosed |
| WO-2022061172-A2 | NUCLEIC ACID DETECTION USING A NUCLEASE ACTUATOR | THE JOHNS HOPKINS UNIVERSITY (US) | 2022-03-24 | — | — | WO | disclosed |