Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 3/20 | 0.47 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.42 |
| ▸ | DRD2 | P14416 | 4/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | PNMT | P11086 | 1/20 | 0.40 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.40 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.40 |
| ▸ | TACR1 | P25103 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | RXRA | P19793 | 1/20 | 0.38 |
| ▸ | RXRB | P28702 | 1/20 | 0.38 |
| ▸ | RXRG | P48443 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL40091 | 1.00 | GRIN2B (0.47) | GRIN2BGRIN1SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL20472428 | 0.86 | GRIN2B (0.43) | GRIN2BGRIN1SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL30580173 | 0.84 | MPL (0.45) | GRIN2BGRIN1SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL1299443 | 0.84 | TAAR1 (0.58) | GRIN2BGRIN1SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL2094155 | 0.84 | PNMT (0.38) | GRIN2BGRIN1SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL4550818 | 0.84 | MPL (0.45) | GRIN2BGRIN1SLC6A3SLC6A2SLC6A4 | |
| Hydrochloric Acid SCHEMBL2715685 | 0.82 | MPL (0.44) | GRIN2BGRIN1SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL27493207 | 0.82 | GRIN2B (0.41) | GRIN2BGRIN1SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL2088592 | 0.81 | TAAR1 (0.46) | GRIN2BGRIN1SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL1715651 | 0.80 | IDO1 (0.58) | GRIN2BGRIN1SLC6A3SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250376457-A1 | DICHLOROPHENOL HSD17B13 INHIBITORS AND USES THEREOF | INIPHARM INC (US) | 2025-12-11 | — | — | US | disclosed |
| WO-2025093589-A1 | HETEROARYL AMIDE DERIVATIVES AS SODIUM CHANNEL INHIBITORS | CHIESI FARMACEUTICI S.P.A. (IT) | 2025-05-08 | — | — | WO | disclosed |
| EP-4469451-A1 | 2-SUBSTITUTED THIAZOLE HSD17B13 INHIBITORS AND USES THEREOF | Inipharm, Inc. (US) | 2024-12-04 | — | — | EP | disclosed |
| CN-119032090-A | 2-Substituted thiazole HSD17B13 inhibitors and uses thereof | 伊尼制药公司 | 2024-11-26 | — | — | CN | disclosed |
| CN-118271234-A | Piperidine derivative, composition and application thereof | 上海京新生物医药有限公司 | 2024-07-02 | — | — | CN | disclosed |
| CN-118271197-A | Cyclohexylamine derivative, and composition and application thereof | 上海京新生物医药有限公司 | 2024-07-02 | — | — | CN | disclosed |
| CN-112673001-B | Indazole carboxamides as kinase inhibitors | 百时美施贵宝公司 | 2024-06-25 | — | — | CN | disclosed |
| CN-115135648-B | Dihydronaphthyridones, preparation method and medical application thereof | 劲方医药科技(上海)有限公司 | 2024-02-09 | — | — | CN | disclosed |
| CN-116670118-A | Dichlorophenol HSD17B13 inhibitor and application thereof | 伊尼制药公司 | 2023-08-29 | — | — | CN | disclosed |
| WO-2023146897-A1 | 2-SUBSTITUTED THIAZOLE HSD17B13 INHIBITORS AND USES THEREOF | INIPHARM, INC. (US) | 2023-08-03 | — | — | WO | disclosed |
| CN-111566103-B | Aminoimidazopyrazines as kinase inhibitors | 百时美施贵宝公司 | 2023-06-23 | — | — | CN | disclosed |
| CN-113508109-B | Substituted heterocyclic amide compound, preparation method and medical application thereof | 劲方医药科技(上海)有限公司 | 2023-02-10 | — | — | CN | disclosed |
| CN-115135648-A | Dihydronaphthyridinone compounds, preparation method and medical application thereof | 劲方医药科技(上海)有限公司 | 2022-09-30 | — | — | CN | disclosed |
| CN-110520423-B | Aminotriazolopyridines as kinase inhibitors | 百时美施贵宝公司 | 2022-08-23 | — | — | CN | disclosed |
| CN-114668761-A | Novel ferroportin inhibitors | 威佛（国际）股份公司 | 2022-06-28 | — | — | CN | disclosed |
| CN-112313234-B | Pyrazolo-triazolopyrimidine derivatives as A2A receptor antagonists | 百济神州有限公司 | 2022-04-29 | — | — | CN | disclosed |
| CN-108290878-B | Novel ferroportin inhibitors | 威佛（国际）股份公司 | 2022-04-26 | — | — | CN | disclosed |
| WO-2022061155-A1 | IMIDAZOPYRIDAZINE AND IMIDAZOPYRAZINE COMPOUNDS AS INHIBITORS OF CDK7 | THE TRANSLATIONAL GENOMICS RESEARCH INSTITUTE (US) | 2022-03-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250376457-A1 | DICHLOROPHENOL HSD17B13 INHIBITORS AND USES THEREOF | HSD17B1, HSD17B3, HSD17B13 | GRIN2B 3479/4885GRIN1 4045/4885SLC6A3 1259/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.