Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | SCN5A | Q14524 | 4/20 | 0.44 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.40 |
| ▸ | SCN10A | Q9Y5Y9 | 4/20 | 0.39 |
| ▸ | ACP1 | P24666 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | PSD | A5PKW4 | 1/20 | 0.37 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29413795 | 0.82 | NPC1 (0.48) | MAPTKDM4EL3MBTL1NPY5RCYP1A2 | |
| SCHEMBL29413855 | 0.81 | FAAH (0.34) | MAPTMAPK1KDM4EGAAL3MBTL1 | |
| SCHEMBL29413827 | 0.79 | NPC1 (0.43) | MAPTMAPK1KDM4EGAACYP1A2 | |
| SCHEMBL29413805 | 0.78 | KDR (0.40) | MAPTMAPK1KDM4EL3MBTL1CYP1A2 | |
| SCHEMBL29413821 | 0.77 | CA1 (0.40) | MAPTKDM4ECYP1A2NPC1ALDH1A1 | |
| SCHEMBL17290376 | 0.76 | MAPT (0.48) | MAPTMAPK1KDM4EGAAL3MBTL1 | |
| SCHEMBL29413798 | 0.74 | RAD51 (0.44) | MAPTGAAL3MBTL1NPY5RPOLB | |
| SCHEMBL29413782 | 0.71 | — | — | |
| SCHEMBL31199041 | 0.70 | MAPT (0.36) | MAPTKDM4EL3MBTL1CYP1A2ADORA3 | |
| SCHEMBL15814004 | 0.69 | MAPT (0.62) | MAPTMAPK1KDM4EGAAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108558833-B | Pyrazole alcohol compound, pharmaceutical composition thereof and application thereof in medicines | 贵州医科大学 | 2022-03-04 | — | — | CN | disclosed |