Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.62 |
| ▸ | GAA | P10253 | 4/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | APP | P05067 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | SNCA | P37840 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1239861 | 1.00 | MAPT (0.62) | MAPTGAAALDH1A1KMT2AKDM4E | |
| SCHEMBL20062968 | 0.86 | KMT2A (0.55) | MAPTKMT2AMEN1RAD52RAB9A | |
| SCHEMBL16035726 | 0.85 | TDO2 (0.49) | MAPTGAAALDH1A1KMT2AKDM4E | |
| SCHEMBL16089612 | 0.85 | TDO2 (0.49) | MAPTGAAALDH1A1KMT2AKDM4E | |
| SCHEMBL2182638 | 0.83 | GRM5 (0.42) | MAPTGAAALDH1A1KMT2AKDM4E | |
| SCHEMBL22497669 | 0.82 | HDAC1 (0.56) | MAPTGAAALDH1A1KMT2AKDM4E | |
| SCHEMBL4760604 | 0.79 | MAPT (0.69) | MAPTGAAALDH1A1KMT2AKDM4E | |
| SCHEMBL29414655 | 0.79 | MAPT (0.69) | MAPTGAAALDH1A1KMT2AKDM4E | |
| SCHEMBL2503575 | 0.78 | HDAC1 (0.46) | ALDH1A1KMT2AKDM4EMEN1HDAC3 | |
| SCHEMBL13270194 | 0.78 | KMT2A (0.51) | MAPTALDH1A1KMT2AKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111747933-B | Substituted 1,3, 5-triazine compound, composition and application thereof | 吉林省元合电子材料有限公司 | 2022-03-01 | — | — | CN | disclosed |